NDLI: Smooth enucleation of bovine oocyte by microrobot with local flow speed control in microchannel

Content Provider	IEEE Xplore Digital Library
Author	Lin Feng Hagiwara, M. Ichikawa, A. Kawahara, T. Arai, F.
Copyright Year	2012
Description	Author affiliation: Nagoya University, Japan (Lin Feng; Ichikawa, A.; Arai, F.) \|\| Kyushu Institute of technology, Japan (Kawahara, T.) \|\| UCLA, Japan (Hagiwara, M.)
Abstract	In this study, we present a smooth enucleation process on a microfluidic chip. To improve the success rate of enucleation and increasing the potential viability of the enucleated oocyte, a microfluidic system is specially designed. Magnetically driven MicroTool (MMT) control the flow distribution in the microchamber. Designed microchannel with height difference is for the purpose of confining oocyte with its nucleus located in the withdrawal microchannel to achieve the high precision control in cutting volume. By utilizing these aspects, first, oocytes are sequentially loaded to the operation port; MMT constrains the oocyte location and controls the distribution of micro flow simultaneously letting hydraulic force cut off the nucleus from the oocyte. Enucleated oocyte is smooth in shape and incision is neat. With cutting volume control, this system can achieve high-speed enucleation with less cutting volume while removing the nucleus. Since the flow distribution could be managed by MMT significantly, therefore, the new system is proposed here to show advantages by the means of operation speed, cutting precision and great potentiality on continuous cutting process.
Starting Page	944
Ending Page	949
File Size	1383081
Page Count	6
File Format	PDF
ISBN	9781467317375
ISSN	21530858
e-ISBN	9781467317368
DOI	10.1109/IROS.2012.6386112
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-10-07
Publisher Place	Portugal
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Microchannel Force Fluids Educational institutions Microfluidics Surface treatment Silicon
Content Type	Text
Resource Type	Article
Subject	Control and Systems Engineering Computer Science Applications Computer Vision and Pattern Recognition Software

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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