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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | N'Doye, I. Voos, H. Darouach, M. Schneider, J.G. Knauf, N. |
| Copyright Year | 2012 |
| Description | Author affiliation: University of Luxembourg, Luxembourg Centre for Systems Biomedicine, 7, Avenue des hauts Fournaux L-4362 Belval, Luxembourg (Schneider, J.G.) || Centre Hospitalier du Nord, 120, Avenue Salentiny L-9080 Ettelbruck, Luxembourg (Knauf, N.) || University of Luxembourg, Faculté des Sciences, de la Technologie et de la Communication, 6, rue Richard Coudenhove-Kalergi, L-1359 Luxembourg (N'Doye, I.; Voos, H.) || Centre de Recherche en Automatique de Nancy (CRAN - UMR 7039) Université de Lorraine - CNRS, IUT de Longwy, 186 rue de Lorraine 54400 Cosnes et Romain, France (Darouach, M.) |
| Abstract | Diabetes is a long-term disease during which the body's production and use of the insulin are impaired, causing glucose concentration level to increase in the bloodstream. The blood glucose dynamics is described using the generalized minimal model structure for the intravenously infused insulin-blood glucose, which can represent a wide variety of diabetic patients. In this paper, it is an attempt to incorporate fractional-order derivative into the mathematical minimal model of glucose-insulin system dynamics and it is still an interesting challenge to determine, mathematically, how the order of a fractional differential system affects the dynamics of system. The paper presents the asymptotical stabilization problem of nonlinear fractional-order glucose-insulin systems. A static output feedback control is considered for the problem. Sufficient conditions for the asymptotical stabilization of the nonlinear fractional-order glucose-insulin system are derived in terms of linear matrix inequalities (LMIs) formulation by using the fractional Lyapunov direct method where the fractional-order α belonging to 0 < α < 1. Finally, numerical simulations are carried out to illustrate our proposed results. These numerical simulations show that the nonlinear fractional-order glucose-insulin systems are, at least, as stable as their integer order counterpart. |
| Starting Page | 589 |
| Ending Page | 594 |
| File Size | 561572 |
| Page Count | 6 |
| File Format | |
| ISBN | 9781467316644 |
| e-ISBN | 9781467316668 |
| DOI | 10.1109/IECBES.2012.6498043 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2012-12-17 |
| Publisher Place | Malaysia |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Minimal model of glucose-insulin Fractional-order model Lyapunov fractional Diabetes control Static output state feedback Linear matrix inequality (LMI) Fractional calculus Asymptotical stabilization |
| Content Type | Text |
| Resource Type | Article |
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