NDLI: Comparing of various collagens for application of cartilage tissue engineering

Content Provider	IEEE Xplore Digital Library
Author	Sang-Hyug Park Tongjin Song Tae Soo Bae Ara, J. Sun Hee Hwang Gon Khang Byoung-Hyun Min Park, S.R.
Copyright Year	2012
Description	Author affiliation: Department of Orthopeadic Surgery, Medical School, Ajou University, Suwon-si, Gyeonggi-do 443-749, Republic of Korea (Ara, J.) \|\| Department of Biomedical Engineering, Jungwon University, Chungcheongbuk-do 367-805, Republic of Korea (Sang-Hyug Park; Tongjin Song; Tae Soo Bae) \|\| Department of Physiology, College of Medicine, Inha University, Incheon 402-751, Republic of Korea (Park, S.R.) \|\| Department of Biomedical Engineering, Kyung Hee University, Yongin-si, Gyeonggi-do 446-701, Republic of Korea (Sun Hee Hwang; Gon Khang; Byoung-Hyun Min)
Abstract	Mammalian collagens have been used as a base material for collagen matrices in tissue engineering applications. However, collagens of aquatic animals and human sources can potentially be utilized as a safe and viable substitute, because collagen products of bovine origin have been shown to be contaminated with some diseases. In the present study, we prepared and investigated collagen materials from several sources (bovine skin, porcine skin, amniotic membrane and starfish) as matrix biomaterials. Detailed investigations on their physicochemical and biological properties, such as amino acid composition, thermal transition temperature, molar mass, IR spectra, and cell response, suggested strong relations between their amino acid composition and intermolecular structure, thermal property, and cell response. Selectively, an amniotic membrane collagen scaffold was evaluated for cartilage tissue engineering in three types of three-dimensional 3D culture (sponge, gel and micro bead forms) and compared with a bovine matrix. Results showed that amniotic membrane collagen has a potential as an alternative source of collagen for use in tissue engineering.
Starting Page	76
Ending Page	79
File Size	1717459
Page Count	4
File Format	PDF
ISBN	9781467316644
e-ISBN	9781467316668
DOI	10.1109/IECBES.2012.6498134
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-12-17
Publisher Place	Malaysia
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Porcine Amniotic membrane Bovine Collagen scaffold Tissue engineering Starfish
Content Type	Text
Resource Type	Article

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