NDLI: First-pass MRI compartmental analysis at the chronic stage of infarction: myocardial flow reserve parametric map

Content Provider	IEEE Xplore Digital Library
Author	Germain, P. Baruthio, J. Roul, G. Dumitresco, B.
Copyright Year	2000
Description	Author affiliation: Fac. de Med., Strasbourg, France (Germain, P.)
Abstract	The regional myocardial flow and flow reserve (MFR) have been assessed using compartmental analysis of Gd-enhanced MRI first-pass data in 7 patients with atypical chest pain, and in 15 patients with previous transmural myocardial infarction. The FE product (Flow /spl times/ Extraction coefficient), derived from the modified KeTy equation, has been measured in the regions corresponding to the Tetrofosmine-SPECT fixed defect and in the remote normal regions. The FE product at rest and hyperhemic FE product were similar in healed revascularised tissues (70.5/spl plusmn/15.6 and 112.5/spl plusmn/19.5 ml/mn/100 g respectively) and in the normal myocardium (76.2/spl plusmn/18.3 and 142.2/spl plusmn/33.0 respectively). In contrast the FE index (48.8/spl plusmn/15.2 and 60.7/spl plusmn/18.0 respectively, p<0.01 versus the two previous groups) and the MFR (1.27/spl plusmn/0.20 vs. 1.91/spl plusmn/0.29 in normal regions) were reduced in healed fibrotic tissues when the infarct-related artery remained occluded. Myocardial flow reserve maps allowed the authors to identify correctly the regions corresponding to an occluded infarct-related artery.
Starting Page	675
Ending Page	678
File Size	609419
Page Count	4
File Format	PDF
ISBN	0780365577
ISSN	02766547
DOI	10.1109/CIC.2000.898614
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2000-09-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Magnetic resonance imaging Myocardium Blood Iron Arteries Equations Fluid flow measurement Plasma measurements History Pain
Content Type	Text
Resource Type	Article

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