NDLI: Myocardial perfusion evaluation with T2-prepared gradient echo blood oxygen level dependent imaging at 3 Tesla

Content Provider	IEEE Xplore Digital Library
Author	Shea, S.M. Schirf, B.E. Bi, X. Tang, R. Lu, B. Omary, R.A. Li, D.
Copyright Year	2004
Description	Author affiliation: Dept. of Biomed. Eng., Northwestern Univ., Evanston, IL, USA (Shea, S.M.)
Abstract	Detecting myocardial perfusion reserve differences using blood oxygen level dependent (BOLD) MRI may improve at 3 T vs 1.5 T. Stenosis-model dogs (n=3) were imaged at 3 T using a gradient echo sequence (GRE) with T2-preparation for BOLD weighting and without as a control. 3 short-axis slices were acquired at rest and during stenosis and adenosine-induced stress with fluorescent microspheres injected to provide blood flow information. Quantitative measurements showed significant changes for BOLD images (left anterior descending (LAD) or septal vs left circumflex (LCX) regions=1.20/spl plusmn/0.11; LAD vs septal regions=1.03/spl plusmn/0.06; p<0.001), but not for control images (LAD or septal vs LCX regions=1.01/spl plusmn/0.04; LAD vs septal regions=0.99/spl plusmn/0.05; p=0.09). BOLD MR vs microsphere measured flow (MR=0.053*SPHERE+1.03) showed good correlation (R=0.61). In conclusion, 3 T BOLD imaging was able to identify myocardial perfusion changes.
Starting Page	145
Ending Page	148
File Size	836037
Page Count	4
File Format	PDF
ISBN	0780389271
DOI	10.1109/CIC.2004.1442892
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-09-19
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Myocardium Oxygen Magnetic resonance imaging Biomedical imaging Dogs Blood flow Fluorescence Biomedical measurements Fluid flow measurement Heart
Content Type	Text
Resource Type	Article

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