NDLI: A simple model for the simulation of low frequency heart rate variability waves

Content Provider	IEEE Xplore Digital Library
Author	Leor-Librach, R.J. Bobrovsky, B.Z. Eliash, S. Kaplinsky, E.
Copyright Year	2000
Description	Author affiliation: The Heart Inst., Sanz Med. Center, Netanya, Israel (Leor-Librach, R.J.)
Abstract	The purpose of this study was mathematical modeling of the low frequency heart rate variability wave (LFHR) and its response to isoproterenol (ISP) infusion. In a previous study the authors found that the steady-state HR can be described as a hyperbolic power function of the steady-state ISP flow rate. This dependency was coupled with a first order difference equation to form a pharmacodynamic model that reliably describes the relationship between filtered HR and ISP flow for any arbitrary form of ISP flow function. In the authors' present study they used the filtered-HR-ISP model as part of a proportional integral derivative control loop and showed that this new simple model can simulate LFHR waves. When using filtered and smoothed HR from the experiments as dynamic set-point for the controller the authors found high correlation between LFHR amplitude (R=0.9) and frequency (R=0.87) of the model and the experimental results. This new model can be used for better understanding of the dynamic properties of LFHR waves. It may also be used as a wave generator for testing new methods for the appreciation of LFHR waves.
Starting Page	809
Ending Page	811
File Size	257117
Page Count	3
File Format	PDF
ISBN	0780365577
ISSN	02766547
DOI	10.1109/CIC.2000.898648
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2000-09-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Frequency Heart rate Steady-state Mathematical model Heart rate variability Difference equations PD control Pi control Proportional control Testing
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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