NDLI: Effects of cancer cell metastatic potential on intracellular mechanics

Content Provider	IEEE Xplore Digital Library
Author	Goldstein, D. Weihs, D.
Copyright Year	2010
Description	Author affiliation: Faculty of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa 3200, Israel (Goldstein, D.; Weihs, D.)
Abstract	Understanding the unique mechanical properties of living cells in general, and specifically those of metastatic cancer cells, can lead to major developments in treatment and prevention of diseases. We combine cell micromechanics measurements with cell biology techniques to elucidate the mechanical response of cells. We focus on cells with different metastatic potentials and their response to cytoskeletal perturbation. We have observed different mechanical responses to microtubule disruption in cells with different metastatic potential. The response was different as compared to each cell lines' control, although the control cells exhibited similar mechanical behavior. Our results may provide a more quantitative measure for metastatic potential in cells, as compared to the common medical definition.
Starting Page	000226
Ending Page	000228
File Size	293118
Page Count	3
File Format	PDF
ISBN	9781424486816
e-ISBN	9781424486823
DOI	10.1109/EEEI.2010.5661964
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-11-17
Publisher Place	Israel
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Breast cancer Particle measurements Atmospheric measurements Biomedical measurements Probes Morphology
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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