NDLI: Investigation of coding structure in DNA

Content Provider	IEEE Xplore Digital Library
Author	Rosen, G.L. Moore, J.D.
Copyright Year	2003
Description	Author affiliation: Center for Signal & Image Process., Georgia Inst. of Technol., GA, USA (Rosen, G.L.; Moore, J.D.)
Abstract	We have all heard the term "cracking the genomic code", but is DNA a code in the information theoretic sense? The coined term "genetic code" maps nucleotide triplets (codons) to amino acids. However, this is in a computer coding sense because a codon instruction is performed to output an amino acid sequence. We examine methods to detect redundant coding structures in DNA. First, a finite field framework for a nucleotide symbolic sequence is presented; then approaches to finding the sequence structure associated with error correcting codes are examined. We compare a previously proposed parity-check vector search method to a novel subspace partitioning algorithm. The subspace partitioning algorithm is a general approach to finding any linear coding redundancy. Our method provides an easy way of visualizing coding potential in DNA sequences as shown from the test data.
Sponsorship	IEEE Signal Process, Soc
File Size	323931
File Format	PDF
ISBN	0780376633
ISSN	15206149
DOI	10.1109/ICASSP.2003.1202370
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2003-04-06
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	DNA Sequences Amino acids Partitioning algorithms Genomics Bioinformatics Genetics Computer aided instruction Galois fields Error correction codes
Content Type	Text
Resource Type	Article

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