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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Tahirbegi, Islam Bogachan Mir, Mònica Samitier, Josep |
| Description | Country affiliation: Spain Author Affiliation: Tahirbegi IB ( Nanobioengineering Laboratory, Institute for Bioengineering of Catalonia (IBEC), Baldiri Reixac, 10-12, Barcelona 08028, Spain.) |
| Abstract | The low pH in the gastric juice of the stomach makes it difficult to fabricate stable and functional all-solid-state pH ISE sensors to sense ischemia, mainly because of anion interference and adhesion problem between the ISE membrane and the electrode surface. In this work, the adhesion of ISE membrane on solid surface at low pH was improved by modifying the surface with a conductive substrate containing hydrophilic and hydrophobic groups. This creates a stable and robust candidate for low pH applications. Moreover, anion interference problem at low pH was solved by integration of all-solid-state ISE and internal reference electrodes on an array. So, the same tendencies of anion interferences for all-solid-state ISE and all-solid-state reference electrodes cancel each other in differential potentiometric detection. The developed sensor presents a novel all-solid-state potentiometric, miniaturized and mass producible pH ISE sensor for detecting ischemia on the stomach tissue on an array designed for endoscopic applications. |
| ISSN | 09565663 |
| Issue Number | 1 |
| Volume Number | 40 |
| e-ISSN | 18734235 |
| Journal | Biosensors and Bioelectronics |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2013-02-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Conductometry Instrumentation Ion-selective Electrodes Ischemia Diagnosis Physiopathology Prostheses And Implants Stomach Blood Supply Animals Computer Systems Humans Hydrogen-ion Concentration Miniaturization Monitoring, Ambulatory Journal Article Research Support, Non-u.s. Gov't Discipline Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry |
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