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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Ingle, Aviraj Malhotra, Nitesh Narang, Jagriti Singhal, Chaitali Mathur, Ashish Chakraborty, Dhritiman Pundir, Chandra S. Anil, Anusree |
| Description | Author Affiliation: Narang J ( Amity Institute of Nanotechnology, Amity University, Noida, UP, India. Electronic address: jags_biotech@yahoo.co.in.); Malhotra N ( Amity Institute of Physiotherapy, Amity University, Noida, UP, India. Electronic address: malhotra.nitesh@gmail.com.); Singhal C ( Amity Institute of Nanotechnology, Amity University, Noida, UP, India.); Mathur A ( Amity Institute of Nanotechnology, Amity University, Noida, UP, India.); Chakraborty D ( Amity Institute of Nanotechnology, Amity University, Noida, UP, India.); Anil A ( Amity Institute of Nanotechnology, Amity University, Noida, UP, India.); Ingle A ( Amity Institute of Nanotechnology, Amity University, Noida, UP, India.); Pundir CS ( Department of Biochemistry, MD University, Rohtak, Haryana, India.) |
| Abstract | The present study was aimed to develop an ultrasensitive technique for electroanalysis of ketamine; a date rape drug. It involved the fabrication of nano-hybrid based electrochemical micro fluidic paper-based analytical device (EµPADs) for electrochemical sensing of ketamine. A paper chip was developed using zeolites nanoflakes and graphene-oxide nanocrystals (Zeo-GO). EµPAD offers many advantages such as facile approach, economical and potential for commercialization. Nanocrystal modified EµPAD showed wide linear range 0.001-5nM/mL and a very low detection limit of 0.001nM/mL. The developed sensor was tested in real time samples like alcoholic and non-alcoholic drinks and found good correlation (99%). The hyphenation of EµPAD integrated with nanocrystalline Zeo-GO for detection of ketamine has immense prospective for field-testing platforms. An extensive development could be made for industrial translation of this fabricated device. |
| ISSN | 09565663 |
| Volume Number | 88 |
| e-ISSN | 18734235 |
| Journal | Biosensors and Bioelectronics |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2017-02-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Anesthetics, Dissociative Analysis Beverages Electrochemical Techniques Instrumentation Graphite Chemistry Ketamine Point-of-care Systems Zeolites Electrodes Equipment Design Limit Of Detection Microfluidic Analytical Techniques Nanoparticles Ultrastructure Oxides Paper Evaluation Studies Journal Article Discipline Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry |
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