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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Shirai, Yoshihito Ma, Kedong Maeda, Toshinari You, Huiyan |
| Description | Author Affiliation: Ma K ( College of Environmental and Chemical Engineering, Dalian University, Dalian 116622, People's Republic of China) |
| Abstract | The development of a low-cost polymer-grade L-lactic acid production process was achieved in this study. Excess sludge hydrolyzate (ESH) was chosen as nutrient source for the objective of reducing nutrient cost in lactic acid production. 1% of ESH had high performance in lactic acid production relative to 2g/l yeast extract (YE) while the production cost of ESH was much lower than that of YE, indicating ESH was a promising substitute of YE. By employing a thermophilic strain of Bacillus coagulans (NBRC 12583), non-sterilized batch and repeated batch L-lactic acid fermentation was successfully performed, and the optical purity of L-lactic acid accumulated was more than 99%. Moreover, the factors associated with cell growth and lactic acid fermentation was investigated through a two-stage lactic acid production strategy. Oxygen played an important role in cell growth, and the optimal condition for cell growth and fermentation was pH 7.0 and 50°C. |
| ISSN | 09608524 |
| Volume Number | 151 |
| e-ISSN | 18732976 |
| Journal | Bioresource Technology |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2014-01-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Bacillus Metabolism Biotechnology Methods Fermentation Lactic Acid Biosynthesis Optical Phenomena Sewage Microbiology Temperature Aerobiosis Drug Effects Anaerobiosis Cytology Growth & Development Batch Cell Culture Techniques Cell Proliferation Feasibility Studies Glucose Hydrogen-ion Concentration Nitrogen Pharmacology Oxygen Journal Article Discipline Bioresource |
| Content Type | Text |
| Resource Type | Article |
| Subject | Waste Management and Disposal Medicine Environmental Engineering Renewable Energy, Sustainability and the Environment Bioengineering |
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