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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Schroeder, Carsten Tariq, Khurram Hao, Zhonglin Biddinger, Paul |
| Description | Author Affiliation: Hao Z ( Department of Medicine, Cancer Center, Georgia Regents University, Medical College of Georgia, Augusta, Georgia, USA.); Biddinger P ( Department of Pathology, Georgia Regents University, Augusta, Georgia, USA.); Schroeder C ( Department of Surgery, Georgia Regents University, Augusta, Georgia, USA.); Tariq K ( Department of Medicine, Georgia Regents University, Augusta, Georgia, USA.) |
| Abstract | A 58-year-old woman, a heavy smoker, was diagnosed with stage III squamous cell lung cancer. She was treated with concurrent chemotherapy and radiotherapy, with partial response. 2â months later, she had haemoptysis caused by brisk bleeding from the radiated right upper lobe. Fortunately, her bleed was self-limited. 4â months later, a rapidly enlarging renal mass was discovered and turned out to be metastatic from the lung primary. Second-line chemotherapy with docetaxel and ramucirumab did not have effects on the renal mass after 2 cycles. Despite not being eligible for a durvalumab trial because of lack of PD-L1 expression, she had a meaningful response to nivolumab. Once every 2â weeks, infusion of nivolumab resulted in rapid tumour shrinkage in multiple areas. In the next few months, she experienced a variety of side effects, some of which were potentially life-threatening. She had disease progression 9â months into treatment. |
| Journal | BMJ Case Reports |
| Volume Number | 2016 |
| e-ISSN | 1757790X |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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