NDLI: The bat gene of Halobacterium halobium encodes a trans-acting oxygen inducibility factor.

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The bat gene of Halobacterium halobium encodes a trans-acting oxygen inducibility factor.

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The bat gene of Halobacterium halobium encodes a trans-acting oxygen inducibility factor.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Betlach, M. C. Gropp, F.
Description	Author Affiliation: Gropp F ( Department of Biochemistry and Biophysics, University of California, San Francisco 94143.);
Abstract	Oxygen and light affect the expression of the bacterioopsin gene (bop), which encodes a light-driven proton pump in the purple membrane of Halobacterium halobium. This response is thought to be mediated by a set of genes located adjacent to the bop gene. DNA fragments containing either the bop gene or the entire bop gene cluster reversed the phenotype of purple membrane-deficient strains with mutations in the bop gene. Purple membrane synthesis was constitutive in one of these strains transformed with the bop gene alone. The same strain transformed with the bop gene cluster was inducible by low oxygen tension. Moreover, another strain that constitutively expresses purple membrane remained constitutive when transformed with the bop gene alone but the phenotype of the strain changed to inducible when transformed with the bop gene cluster. Additional experiments have confirmed that one of the genes of the bop gene cluster, the bat gene, encodes a trans-acting factor that is necessary and sufficient to confer inducibility of purple membrane synthesis by low oxygen tension.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	12
Volume Number	91
Language	English
Publisher	National Academy of Sciences
Publisher Date	1994-07-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Bacteriorhodopsins Genetics Gene Expression Regulation, Bacterial Genes, Bacterial Genes, Regulator Halobacterium Salinarum Operon Oxygen RNA, Messenger Sequence Homology, Amino Acid Comparative Study Research Support, U.S. Gov't, P.H.S. Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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