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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Phillips, R. L. Olhoft, P. Kaeppler, S. M. |
| Description | Author Affiliation: Phillips RL ( Department of Agronomy, University of Minnesota, St. Paul 55108.); |
| Abstract | Plants regenerated from relatively undifferentiated callus cultures possess a vast array of genetic changes. Such variations can result in useful agricultural and horticultural products. For other purposes, however, variations in traits other than those of interest may be undesirable--for example, using cultured cells for genetic engineering. Any steps made toward understanding the basis of tissue culture-induced genetic variation should be helpful in developing a more stable and manipulatable somatic cell system. This review provides a glimpse at the specific kinds of genetic changes encountered among regenerated plants and their progeny. Included among these variations are cytosine methylation alterations of the genome. The repeat-induced point mutation (RIP) phenomenon, reported for filamentous fungi, is invoked to provide a framework to consider the origin of variation in plant tissue cultures. |
| ISSN | 00278424 |
| e-ISSN | 10916490 |
| Journal | Proceedings of the National Academy of Sciences of the United States of America |
| Issue Number | 12 |
| Volume Number | 91 |
| Language | English |
| Publisher | National Academy of Sciences |
| Publisher Date | 1994-07-01 |
| Publisher Place | United States |
| Access Restriction | Open |
| Subject Keyword | Plant Cells Plants Genetics Repetitive Sequences, Nucleic Acid 5-Methylcytosine Culture Techniques Cytosine Analogs & Derivatives Metabolism DNA Methylation Point Mutation Research Support, U.S. Gov't, Non-P.H.S. Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
| Subject | Multidisciplinary |
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