NDLI: Heterogeneities in the transmission of infectious agents: implications for the design of control programs.

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Heterogeneities in the transmission of infectious agents: implications for the design of control programs.

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Heterogeneities in the transmission of infectious agents: implications for the design of control programs.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Chandiwana, S. K. Hii, J. L. Woolhouse, M. E. Dye, C. Quinnell, R. J. Garnett, G. P. Charlwood, J. D. Smith, T. Anderson, R. M. Watts, C. H. Etard, J. F. Hagan, P. Ndhlovu, P. D.
Description	Author Affiliation: Woolhouse ME ( Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, United Kingdom. mejw@vax.ox.ac.uk);
Abstract	From an analysis of the distributions of measures of transmission rates among hosts, we identify an empirical relationship suggesting that, typically, 20% of the host population contributes at least 80% of the net transmission potential, as measured by the basic reproduction number, R0. This is an example of a statistical pattern known as the 20/80 rule. The rule applies to a variety of disease systems, including vector-borne parasites and sexually transmitted pathogens. The rule implies that control programs targeted at the 'core' 20% group are potentially highly effective and, conversely, that programs that fail to reach all of this group will be much less effective than expected in reducing levels of infection in the population as a whole.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	1
Volume Number	94
Language	English
Publisher	National Academy of Sciences
Publisher Date	1997-02-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Communicable Disease Control Disease Transmission, Infectious Health Planning Models, Theoretical Animals Disease Vectors HIV Infections Prevention & Control Transmission Leishmaniasis Malaria Schistosomiasis Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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