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Year: 2015 Volume: 56 Issue: Supplementary

Impact of supervised cardiac rehabilitation on urinary albumin excretion in patients with cardiovascular disease.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Kimura, Sahika Ueda, Yuka Ise, Takayuki Yagi, Shusuke Iwase, Takashi Nishikawa, Koji Yamaguchi, Koji Yamada, Hirotsugu Soeki, Takeshi Wakatsuki, Tetsuzo Katoh, Shinsuke Akaike, Masashi Yasui, Natsuo Sata, Masataka
Spatial Coverage	Japan
Description	Author Affiliation: Kimura S ( Department of Cardiovascular Medicine, The University of Tokushima Graduate School of Health Biosciences.)
Abstract	Urinary albumin excretion is a predictor of cardiovascular death. Cardiac rehabilitation (CR) with exercise training (ET) has been shown to improve exercise capacity and prognosis in patients with cardiovascular disease (CVD). However, it remains unclear whether CR reduces urinary albumin excretion in CVD patients. We performed a retrospective, observational study using data obtained from 98 male CVD patients without macroalbuminuria and estimated glomerular filtration rate (eGFR) < 30 mL/minute/1.73 m(2) who participated in CR with ET during hospitalization. Twenty-three patients continued supervised ET for 6 months (supervised group) and 75 patients quit supervised ET (non-supervised group). The supervised ET program consisted of 60 minutes of supervised sessions 1-3 times a week and 30-60 minutes of home exercise at least twice a week. Urinary albumin/creatinine ratio (ACR) was significantly decreased in the supervised group at 6 months after enrollment (43 ± 71 mg/g to 17 ± 20 mg/g creatinine, P < 0.05) but not in the non-supervised group. eGFR was unchanged in the supervised group but was significantly decreased in the non-supervised group (72 ± 18 mL/minute/1.73 m(2) to 67 ± 17 mL/minute/1.73 m(2), P < 0.001). The results of multiple regression analysis showed that only supervised ET was an independent contributor to ΔACR. CR with supervised ET decreased urinary albumin excretion without deterioration of renal function. These findings suggest that continuation of a supervised ET program is associated with reduction in the development of CVD and reduction in cardiovascular morbidity and mortality in CVD patients.
File Format	HTM / HTML
ISSN	13492365
e-ISSN	13493299
Journal	International Heart Journal
Issue Number	1
Volume Number	56
Language	English
Publisher	International Heart Journal Association
Publisher Date	2015-01-01
Publisher Place	Japan
Access Restriction	Open
Subject Keyword	Discipline Cardiology Albuminuria Cardiovascular Diseases Exercise Therapy Organization And Administration Albumins Diagnosis Etiology Metabolism Complications Creatinine Blood Organization & Administration Exercise Tolerance Glomerular Filtration Rate Regression Analysis Retrospective Studies
Content Type	Text
Resource Type	Article
Subject	Cardiology and Cardiovascular Medicine

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