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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Bakry, Fayez A. Eleiwa, Mona E. Taha, Samir A. Ismil, Somya M. |
| Description | Country affiliation: Egypt Author Affiliation: Bakry FA ( Medical Malacology Department, Theodor Bilharz Research Institute, Giza, Egypt fayezbakery@yahoo.com.); Eleiwa ME ( Department of Botany, Cairo University, Cairo, Egypt.); Taha SA ( Department of Zoology, Zagazig University, Zagazig, Egypt.); Ismil SM ( Department of Zoology, Cairo University, Cairo, Egypt.) |
| Abstract | Paraquat has been shown to be a highly toxic compound for humans and animals, and many cases of acute poisoning and death have been reported over the past few decades. The present study was undertaken to evaluate comprehensively herbicides (Paraquat) and some plant extracts to biochemical aspects of Lymnaea natalensis snails. It was found that the exposure of L. natalensis to Paraquat and plant extracts led to a significant reduction in the infectivity of Fasciola gigantica miracidia to the snail. The glucose level in hemolymph of exposed snails was elevated, while the glycogen showed a decrease in soft tissues when compared with the control group. In addition, the activity level of some enzymes representing glycolytic enzymes as hexokinase (HK), pyruvate kinase (PK), phosphofructokinase (PFK), lactate dehydrogenase (LDH), and glucose phosphate isomerase (GPI) in snail's tissues were reduced in response to the treatment. It was concluded that the pollution of the aquatic environment by herbicide would adversely affect the metabolism of the L. natalensis snails. Snails treated with Agave attenuate, Ammi visnaga, and Canna iridiflora plant had less toxic effect compared to snails treated with Paraquat. |
| File Format | HTM / HTML |
| ISSN | 07482337 |
| Issue Number | 1 |
| Volume Number | 32 |
| e-ISSN | 14770393 |
| Journal | Toxicology and Industrial Health |
| Language | English |
| Publisher | Sage Publications |
| Publisher Date | 2016-01-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Occupational Medicine Discipline Toxicology Herbicides Toxicity Lymnaea Drug Effects Paraquat Plant Extracts Animals Fasciola Growth & Development Glucose-6-phosphate Isomerase Metabolism Hexokinase L-lactate Dehydrogenase Lethal Dose 50 Parasitology Phosphofructokinases Phytochemicals Pyruvate Kinase Comparative Study Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health Toxicology |
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