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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Kraehenbuehl, Thomas P. Langer, Robert Ferreira, Lino S. |
| Description | Country affiliation: United States Author Affiliation: Kraehenbuehl TP ( Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.) |
| Abstract | The self-renewal and differentiation of human pluripotent stem cells (hPSCs) have typically been studied in flat, two-dimensional (2D) environments. In this Perspective, we argue that 3D model systems may be needed in addition, as they mimic the natural 3D tissue organization more closely. We survey methods that have used 3D biomaterials for expansion of undifferentiated hPSCs, directed differentiation of hPSCs and transplantation of differentiated hPSCs in vivo. |
| File Format | HTM / HTML |
| ISSN | 15487091 |
| Issue Number | 9 |
| Volume Number | 8 |
| e-ISSN | 15487105 |
| Journal | Nature Methods |
| Language | English |
| Publisher | Nature Publishing Group |
| Publisher Date | 2011-08-30 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Clinical Laboratory Techniques Pluripotent Stem Cells Cytology Animals Biocompatible Materials Chemistry Cell Culture Techniques Methods Cell Differentiation Extracellular Matrix Physiology Humans Receptors, Cell Surface Journal Article Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Biochemistry Molecular Biology Biotechnology |
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