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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Das, Debasish Mazumdar, Prativa Maity, Ashim Tripathy, Satyajit Roy, Somenath Chattopadhyay, Dipankar Misra, Ajay |
| Description | Country affiliation: India Author Affiliation: Das D ( Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore 721102, W.B, India.); Mazumdar P ( Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore 721102, W.B, India.); Maity A ( Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore 721102, W.B, India.); Tripathy S ( Immunology and Microbiology Laboratory, Department of Human Physiology with Community Health, Vidyasagar University, Midnapore 721102, W.B, India.); Roy S ( Immunology and Microbiology Laboratory, Department of Human Physiology with Community Health, Vidyasagar University, Midnapore 721102, W.B, India.); Chattopadhyay D ( Department of Polymer Science and Technology, University College of Science and Technology, 92 APC Road, Kolkata 700009, West Bengal, India.); Misra A ( Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore 721102, W.B, India. Electronic address: ajay@mail.vidyasagar.ac.in.) |
| Abstract | -Napthoflavone (ANF) microstructures of various morphologies were synthesized using reprecipitation method. Sodium Dodecyl Sulfate (SDS) was used as morphology directing agent. The morphologies of the particles were characterized using optical and scanning electron microscopy (SEM). Single crystal data of ANF suggests that the aromatic units of ANF are in parallel slipped conformation in its aggregated form. Photophysical properties of aggregated ANF hydrosol were studied using UV-Vis absorption, steady state and time resolved spectroscopy. Red shift and broadening of UV-Vis spectra of ANF hydrosol are explained due to strong π-π and H-π interactions among the neighboring ANF molecules within the aggregated microstructures. Though ANF is non-luminescent in good solvent, a strong emission is observed in its aggregated state. This aggregation induced emission (AIE) has been explained due to restriction of intramoleculer rotation and large amplitude vibrational modes of ANF in its aggregated state. Our Photophysical study also reveals that AIE effect decreases after an optimum concentration of ANF and this has been explained due to softening of crystal lattice. Cytotoxicity of ANF hydrosol was examined to get an idea of the toxic level of this hydrosol toward cultured normal human cells. It is observed that ANF hydrosol may draw beneficial effect in biological application as it has no higher toxic activity but has antioxidant property. |
| File Format | HTM / HTML |
| ISSN | 10111344 |
| Volume Number | 156 |
| e-ISSN | 18732682 |
| Journal | Journal of Photochemistry and Photobiology B: Biology |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2016-03-01 |
| Publisher Place | Switzerland |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Biology Benzoflavones Pharmacology Chemistry Toxicity Crystallography, X-ray Fluorescent Dyes Humans Molecular Structure Sodium Dodecyl Sulfate Spectrometry, Fluorescence Spectrophotometry, Ultraviolet Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Radiology, Nuclear Medicine and Imaging Biophysics Radiological and Ultrasound Technology Radiation |
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