NDLI: Preparation and characterization of a novel willemite bioceramic

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Zhang, Meili Zhai, Wanyin Chang, Jiang
Description	Author Affiliation: Zhang M ( State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, People's Republic of China.)
Abstract	Willemite $(Zn_{2}SiO_{4})$ ceramics were prepared by sintering the willemite green compacts. The effects of sintering temperature on the linear shrinkage, porosity and mechanical strength of the ceramics were examined. With the sintering temperature increased, the linear shrinkage of the ceramics increased and the porosity decreased. When sintered at 1,300°C, willemite ceramics showed mechanical properties of the same order of magnitude as values for human cortical bone, as measured by bending strength (91.2 ± 4.2 MPa) and Young’s modulus (37.5 ± 1.5 GPa). In addition, the adhesion and proliferation of rabbit bone marrow stromal cells (BMSCs) on willemite ceramics was investigated. The results showed that the ceramics supported cell adhesion and stimulated the proliferation. All these findings suggest that willemite ceramics possess suitable mechanical properties and favorable biocompatibility and might be a promising biomaterial for bone implant applications.
File Format	HTM / HTML
ISSN	09574530
Issue Number	4
Volume Number	21
e-ISSN	15734838
Journal	Journal of Materials Science: Materials in Medicine
Language	English
Publisher	Springer
Publisher Date	2010-04-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Discipline Biomedical Engineering Ceramics Chemistry Chemical Synthesis Oxygen Compounds Silicates Silicon Compounds Zinc Compounds Zinc Animals Biocompatible Materials Pharmacology Body Fluids Physiology Bone Substitutes Cell Adhesion Drug Effects Cell Proliferation Cells, Cultured Hardness Humans Materials Testing Osteoblasts Cytology Rabbits Tensile Strength Evaluation Studies Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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