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Preconception health trajectories and birth weight in a national prospective cohort.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Strutz, Kelly L. Richardson, Liana J. Hussey, Jon M.
Description	Country affiliation: United States Author Affiliation: Strutz KL ( Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27516-2524, USA. strutz@email.unc.edu)
Abstract	PURPOSE: This study was designed to assess the relationship between birth weight and prospectively measured trajectories of preconception health across adolescence and young adulthood in a diverse national cohort of young adult women. METHODS: Data came from Waves I (1994-1995), III (2001-2002), and IV (2007-2008) of the National Longitudinal Study of Adolescent Health. Eligibility was restricted to all the singleton live births (n = 3,436) to female participants occurring between the Wave III (ages 18-26 years) and Wave IV (ages 24-32 years) interviews. Preconception cigarette smoking, overweight/obesity, adequate physical activity, heavy alcohol consumption, and fair/poor self-rated health were measured in adolescence (Wave I) and early adulthood (Wave III) and combined into four-category variables to capture the timing and sequencing of exposure. The outcome measure, birth weight, was classified as low (<2,500 g), normal (2,500-4,000 g), and macrosomic (>4,000 g). RESULTS: Multinomial logistic regression results indicated that adult-onset overweight significantly increased the odds of having a macrosomic birth (odds ratio = 1.56; 95% confidence interval = 1.02-2.38). CONCLUSIONS: This study provides new evidence about the influence of maternal body mass index trajectories on offspring birth weight. Adult-onset overweight/obesity during the transition to adulthood was common in the sample and increased the odds of subsequently delivering a macrosomic infant by 56%. This finding suggests that healthy weight promotion before this transition would confer intergenerational benefits, and supports recommendations for preconception care to address overweight/obesity.
File Format	HTM / HTML
ISSN	1054139X
e-ISSN	18791972
DOI	10.1016/j.jadohealth.2012.03.013
Journal	Journal of Adolescent Health
Issue Number	6
Volume Number	51
Language	English
Publisher	Elsevier
Publisher Date	2012-12-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Pediatrics Birth Weight Health Behavior Preconception Care Statistics & Numerical Data Adolescent Body Mass Index Fetal Macrosomia Epidemiology Health Status Indicators Infant, Low Birth Weight Infant, Newborn Interviews As Topic Logistic Models Obesity Complications Pregnancy Pregnancy Complications Prospective Studies Research Support, N.i.h., Extramural
Content Type	Text
Resource Type	Article
Subject	Public Health, Environmental and Occupational Health Pediatrics, Perinatology and Child Health Psychiatry and Mental Health

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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