NDLI: Moderators of treatment effectiveness for war-affected youth with depression in northern Uganda.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Betancourt, Theresa S. Newnham, Elizabeth A. Brennan, Robert T. Verdeli, Helen Borisova, Ivelina Neugebauer, Richard Bass, Judith Bolton, Paul
Spatial Coverage	Uganda
Description	Country affiliation: United States Author Affiliation: Betancourt TS ( Department of Global Health and Population, Harvard School of Public Health, Boston, Massachusetts 02115, USA. Theresa_Betancourt@harvard.edu)
Abstract	PURPOSE: As we build the evidence base of interventions for depression among war-affected youth, it is critical to understand factors moderating treatment outcomes. The current study investigated how gender and history of abduction by Lord's Resistance Army rebels moderated treatment outcomes for war-affected youth. METHODS: The study-a three-armed, randomized, controlled trial-was conducted with internally displaced war-affected adolescents in northern Uganda. Participants with significant depression symptoms (N = 304; 57% female; 14-17 years of age) were randomly assigned to an interpersonal psychotherapy group (IPT-G), a creative play/recreation group, or a wait-list control condition. Secondary analyses were conducted on data from this randomized controlled trial. RESULTS: A history of abduction by Lord's Resistance Army rebels was reported by 42% of the sample. Gender and abduction history interacted to moderate the effectiveness of IPT-G for the treatment of depression. In the IPT-G intervention arm, treatment effectiveness was greatest among female subjects without an abduction history, with effect size = 1.06. IPT-G was effective for the treatment of depression for both male and female subjects with a history of abduction (effect size = .92 and .50, respectively). Male subjects with no abduction history in IPT-G showed no significant improvement compared with those in the control conditions. CONCLUSIONS: Abduction history and gender are potentially important moderators of treatment effects, suggesting that these factors need to be considered when providing interventions for war-affected youth. IPT-G may be an effective intervention for female subjects without an abduction history, as well as for both male and female former child soldiers, but less so for male subjects without an abduction history.
File Format	HTM / HTML
ISSN	1054139X
Issue Number	6
Volume Number	51
e-ISSN	18791972
Journal	Journal of Adolescent Health
Language	English
Publisher	Elsevier
Publisher Date	2012-12-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Pediatrics Depressive Disorder Therapy Military Personnel Psychology Psychology, Adolescent Psychotherapy Methods Refugees Stress Disorders, Post-traumatic War Adolescent Diagnosis Etiology Female Humans Male Sex Distribution Treatment Outcome Uganda Journal Article Randomized Controlled Trial Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Public Health, Environmental and Occupational Health Pediatrics, Perinatology and Child Health Psychiatry and Mental Health

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