NDLI: Assessment of modified gold surfaced titanium implants on skeletal fixation.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Zainali, Kasra Danscher, Gorm Jakobsen, Thomas Baas, Jorgen Møller, Per Bechtold, Joan E. Soballe, Kjeld
Description	Country affiliation: Denmark Author Affiliation: Zainali K ( Department of Orthopaedics, Orthopaedic Research Center, Aarhus University Hospital, Aarhus C, Denmark. kasrazainali@gmail.com)
Abstract	Noncemented implants are the primary choice for younger patients undergoing total hip replacements. However, the major concern in this group of patients regarding revision is the concern from wear particles, periimplant inflammation, and subsequently aseptic implant loosening. Macrophages have been shown to liberate gold ions through the process termed dissolucytosis. Furthermore, gold ions are known to act in an anti-inflammatory manner by inhibiting cellular NF-κB-DNA binding. The present study investigated whether partial coating of titanium implants could augment early osseointegration and increase mechanical fixation. Cylindrical porous coated Ti-6Al-4V implants partially coated with metallic gold were inserted in the proximal region of the humerus in ten canines and control implants without gold were inserted in contralateral humerus. Observation time was 4 weeks. Biomechanical push out tests and stereological histomorphometrical analyses showed no statistically significant differences in the two groups. The unchanged parameters are considered an improvement of the coating properties, as a previous complete gold-coated implant showed inferior mechanical fixation and reduced osseointegration compared to control titanium implants in a similar model. Since sufficient early mechanical fixation is achieved with this new coating, it is reasonable to investigate the implant further in long-term studies.
File Format	HTM / HTML
ISSN	15493296
e-ISSN	15524965
DOI	10.1002/jbm.a.34307
Journal	Journal of Biomedical Materials Research Part A
Issue Number	1
Volume Number	101
Language	English
Publisher	Wiley
Publisher Date	2013-01-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Microscopy, Electron, Scanning Implants, Experimental Pharmacology Drug Effects Fracture Fixation Physiopathology Discipline Biomedical Engineering Pathology Chemistry Biomechanical Phenomena Animals Titanium Porosity Humerus Bone Remodeling
Content Type	Text
Resource Type	Article
Subject	Ceramics and Composites Metals and Alloys Biomaterials Biomedical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Assessment of modified gold surfaced titanium implants on skeletal fixation

Biofunctional porous anodized titanium implants for enhanced bone regeneration.

Titanium dioxide nanotubes enhance bone bonding in vivo.

Keratin-hydroxyapatite composites: biocompatibility, osseointegration, and physical properties in an ovine model.

Technique for preparation and characterization in cross-section of oral titanium implant surfaces using focused ion beam and transmission electron microscopy.

A new implant with solid core and porous surface: the biocompatability with bone.

Tissue–response to calcium-bonded titanium surface

Comparative in vivo study of commercially pure Ti implants with surfaces modified by laser with and without silicate deposition: biomechanical and scanning electron microscopy analysis.

Enhancing the biological activity of chitosan and controlling the degradation by nanoscale interaction with bioglass.

Assessment of modified gold surfaced titanium implants on skeletal fixation.

Similar Documents

Assessment of modified gold surfaced titanium implants on skeletal fixation

Biofunctional porous anodized titanium implants for enhanced bone regeneration.

Titanium dioxide nanotubes enhance bone bonding in vivo.

Keratin-hydroxyapatite composites: biocompatibility, osseointegration, and physical properties in an ovine model.

Technique for preparation and characterization in cross-section of oral titanium implant surfaces using focused ion beam and transmission electron microscopy.

A new implant with solid core and porous surface: the biocompatability with bone.

Tissue–response to calcium-bonded titanium surface

Comparative in vivo study of commercially pure Ti implants with surfaces modified by laser with and without silicate deposition: biomechanical and scanning electron microscopy analysis.

Enhancing the biological activity of chitosan and controlling the degradation by nanoscale interaction with bioglass.

Assessment of modified gold surfaced titanium implants on skeletal fixation.