NDLI: Quantifying the effect of nanoparticles on As(V) ecotoxicity exemplified by nano-Fe2 O3 (magnetic) and nano-Al2 O3.

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Quantifying the effect of nanoparticles on As(V) ecotoxicity exemplified by nano-Fe2 O3 (magnetic) and nano-Al2 O3.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Hu, Ji Wang, Demin Forthaus, Brett E. Wang, Jianmin
Description	Country affiliation: United States Author Affiliation: Hu J ( Department of Civil, Architectural and Environmental Engineering, Missouri University of Science and Technology, Rolla, MO, USA.)
Abstract	Nano-Fe(2) O(3) (magnetic) and nano-Al(2) O(3) are increasingly used in biomedical fields for cellular labeling and drug delivery, and in the industry as catalysts. However, they may also serve as carriers of toxic contaminants and negatively impact the environment and human health. In the present study, Ceriodaphnia dubia was used to assess the toxicity of these nanoparticles (NPs) with and without the presence of background arsenic(V) (As[V]). The results showed that although these NPs alone did not exhibit significant toxicity in the experimental concentration range, they could significantly enhance the toxicity of As(V). The accumulation of As(V) on nano-Fe(2) O(3) (m) and nano-Al(2) O(3) , as well as the uptake of these NPs in C. dubia, were verified. An inverse relationship between the median lethal concentration (LC50) of the soluble As(V) and the accumulation of NPs in C. dubia was developed. Therefore, the uptake of As(V)-loaded NPs in C. dubia played a key role in enhancing As(V) toxicity.
File Format	HTM / HTML
ISSN	07307268
Issue Number	12
Volume Number	31
e-ISSN	15528618
Journal	Environmental Toxicology and Chemistry
Language	English
Publisher	Wiley
Publisher Date	2012-12-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Research Support, Non-u.s. Gov't Arsenic Environmental Pollutants Models, Chemical Risk Assessment Aluminum Hydroxide Toxicity Discipline Environmental Health Discipline Toxicology Lethal Dose 50 Magnetics Journal Article Drug Delivery Systems Nanoparticles Ferric Compounds Chemistry Animals Daphnia Discipline Chemistry
Content Type	Text
Resource Type	Article
Subject	Environmental Chemistry Health, Toxicology and Mutagenesis

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Synergistic toxic effect of nano-Al2O3 and As(V) on Ceriodaphnia dubia.

Quantifying the effect of nanoparticles on As(V) ecotoxicity exemplified by nano-Fe2 O3 (magnetic) and nano-Al2 O3.

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