NDLI: Prediction of the joint toxicity of five organophosphorus pesticides to Daphnia magna.

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Prediction of the joint toxicity of five organophosphorus pesticides to Daphnia magna.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Zeng, Hong-Hu Lei, Chang-Wen Zhang, Ya-Hui Cao, Ying Liu, Zheng-Tao
Description	Author Affiliation: Zeng HH ( College of Environmental Science and Engineering, Guilin University of Technology, Guilin, 541004, People's Republic of China.)
Abstract	The individual toxicities of five organophosphorus pesticides (dichlorvos, parathion, methyl parathion, malathion and dimethoate) to Daphnia magna were investigated in 24-h immobilization experiments. Using these toxicity data, their combined toxicities were measured in pesticide mixtures designed using either 'equivalent-effect concentration ratios' or 'uniform-design concentration ratios'. The toxicities of mixtures of similarly or dissimilarly acting toxicants are often predicted from the individual toxicities of the component compounds, using one of two distinct biometric models: concentration addition (CA) or independent action (IA). The relative accuracies of the CA and IA models were assessed using the model deviation rate (MDR), which represents the difference between the effect predicted from the individual pesticide concentrations and the observed effect. The mean MDR value of CA was 0.93 (range 0.75-1.31) and the mean value obtained by IA was 3.13 (range 2.52-4.37). We conclude that the CA model is better able to predict the joint toxicities of mixtures of organophosphorus pesticides to D. magna.
File Format	HTM / HTML
ISSN	09639292
Issue Number	10
Volume Number	23
e-ISSN	15733017
Journal	Ecotoxicology
Language	English
Publisher	Springer
Publisher Date	2014-12-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Ecology Discipline Environmental Health Discipline Toxicology Organophosphorus Compounds Toxicity Pesticides Water Pollutants, Chemical Animals Daphnia Dimethoate Dose-response Relationship, Drug Lethal Dose 50 Malathion Methyl Parathion Toxicity Tests Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Medicine Toxicology Management, Monitoring, Policy and Law

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