NDLI: Characteristics of patients with HIV and biopsy-proven acute interstitial nephritis.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Parkhie, Shyam M. Fine, Derek M. Lucas, Gregory M. Atta, Mohamed G.
Description	Country affiliation: United States Author Affiliation: Parkhie SM ( Division of Renal Medicine, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA.)
Abstract	BACKGROUND AND OBJECTIVES: The objective of this study was to describe the characteristics of patients with HIV infection and biopsy-proven acute interstitial nephritis (AIN). DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Pathology reports were reviewed for patients who had HIV infection and underwent renal biopsy at Johns Hopkins Hospital from January 1, 1995, through January 1, 2008. Patients who received a diagnosis of AIN without evidence of HIV-associated nephropathy were identified, and their clinical course was reviewed up to 18 months after biopsy. RESULTS: Of 262 biopsies, 29 (11%) patients who had AIN without evidence of HIV-associated nephropathy were identified. The mean age at the time of biopsy was 47.5 years (range 28 to 71 years), 17 (59%) were men, and 23 (79%) were black. The majority (62%) of patients were on antiretroviral therapy, 59% were current or former intravenous drug users, and 62% had hepatitis C co-infection. Drugs were identified as the cause of AIN in the majority (72%) of cases. Nonsteroidal anti-inflammatory drugs were most commonly implicated, followed by sulfamethoxazole/trimethoprim. Antiretroviral therapy was identified as the cause in only three cases. None of the patients presented with the classic triad of fever, rash, and pyuria, and only seven (24%) patients presented with <1 g/d proteinuria. CONCLUSIONS: In our series, AIN was prevalent (11%) and was often drug induced. AIN should not be excluded from the differential diagnosis on the basis of absence of the classic clinical triad of fever, rash, and pyuria.
File Format	HTM / HTML
ISSN	15559041
e-ISSN	1555905X
DOI	10.2215/CJN.08211109
Journal	Clinical Journal of the American Society of Nephrology
Issue Number	5
Volume Number	5
Language	English
Publisher	American Society of Nephrology
Publisher Date	2010-05-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Acute Disease Adverse Effects Prognosis Complications Risk Factors Drug Therapy Discipline Nephrology Nephritis, Interstitial Hiv Infections Epidemiology Drug Effects Kidney Anti-retroviral Agents Pathology Time Factors Biopsy Etiology
Content Type	Text
Resource Type	Article
Subject	Transplantation Critical Care and Intensive Care Medicine Nephrology Epidemiology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Tubulointerstitial nephropathies in HIV-infected patients over the past 15 years: a clinico-pathological study.

Characteristics of Patients with HIV and Biopsy-Proven Acute Interstitial Nephritis

Biopsy-proven vancomycin-associated interstitial nephritis and acute tubular necrosis.

Renal biopsy findings in acute renal failure in the cohort of patients in the Spanish Registry of Glomerulonephritis.

Acute renal failure from nitrofurantoin-induced acute granulomatous interstitial nephritis.

BK virus nephritis after renal transplantation.

Drug-induced acute interstitial nephritis.

Drug-induced glomerular disease: immune-mediated injury.

Phenazopyridine associated acute interstitial nephritis and review of literature

Characteristics of patients with HIV and biopsy-proven acute interstitial nephritis.

Similar Documents

Tubulointerstitial nephropathies in HIV-infected patients over the past 15 years: a clinico-pathological study.

Characteristics of Patients with HIV and Biopsy-Proven Acute Interstitial Nephritis

Biopsy-proven vancomycin-associated interstitial nephritis and acute tubular necrosis.

Renal biopsy findings in acute renal failure in the cohort of patients in the Spanish Registry of Glomerulonephritis.

Acute renal failure from nitrofurantoin-induced acute granulomatous interstitial nephritis.

BK virus nephritis after renal transplantation.

Drug-induced acute interstitial nephritis.

Drug-induced glomerular disease: immune-mediated injury.

Phenazopyridine associated acute interstitial nephritis and review of literature

Characteristics of patients with HIV and biopsy-proven acute interstitial nephritis.