NDLI: Physiological stress response in white suckers from agricultural drain waters containing pesticides and selenium.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Miller, L. L. Rasmussen, J. B. Palace, V. P. Hontela, A.
Spatial Coverage	Alberta
Description	Author Affiliation: Miller LL ( Department of Biological Sciences, University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, Canada T1K 3M4. lana.miller@uleth.ca)
Abstract	To assess the effect of agriculture drain water, a complex mixture containing pesticides and selenium (Se), on the physiological stress response, white suckers were collected from irrigation return flows in the summer and the fall and subjected to a stress challenge. Water (0.40-26.71microg/L) and muscle Se (0.37-1.52microg/g ww) levels were elevated at two sites and plasma acetylcholinesterase (AChE) activity (a marker of pesticide exposure) was lower in the fall (5.97+/-0.45micromol/min/mL) than the summer (10.73+/-0.73micromol/min/mL). Fish raised plasma cortisol levels in response to the stress challenge 11.8 times above basal levels (12.8+/-4.9ng/mL). Multivariate statistics linked Se exposure to elevated plasma glucose levels, and pesticide exposure to elevated liver glycogen levels generating hypotheses for further testing. This study showed that white suckers accumulated Se from agricultural drain water and the complex mixtures present in the drain water influenced the physiological stress response.
File Format	HTM / HTML
ISSN	01476513
Issue Number	4
Volume Number	72
e-ISSN	10902414
Journal	Ecotoxicology and Environmental Safety
Language	English
Publisher	Elsevier
Publisher Date	2009-05-01
Publisher Place	Netherlands
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Environmental Sciences Agriculture Cypriniformes Physiology Pesticides Toxicity Selenium Stress, Physiological Water Pollutants, Chemical Acetylcholinesterase Blood Alberta Animals Blood Glucose Metabolism Fresh Water Analysis Hydrocortisone Liver Glycogen Muscle, Skeletal Chemistry Reproducibility Of Results Seasons Pharmacokinetics Sodium-potassium-exchanging Atpase Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Pollution Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health

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