| Author |
Caroff, J. Mihalea, C. Klisch, J. Strasilla, C. Berlis, A. Patankar, T. Weber, W. Behme, D. Jacobsen, E. A. Liebig, T. Prothmann, S. Cognard, C. Finkenzeller, T. Moret, J. Spelle, L. |
| Description |
Country affiliation: France Author Affiliation: Caroff J ( From the Interventional Neuroradiology NEURI Center (J.C., C.M., J.M., L.S.), Beaujon Hospital, Clichy, France Jildaz.caroff@bjn.aphp.fr.); Mihalea C ( From the Interventional Neuroradiology NEURI Center (J.C., C.M., J.M., L.S.), Beaujon Hospital, Clichy, France Department of Neurosurgery (C.M.), University of Medicine and Pharmacy 'Victor Babes,' Timisoara, Romania.); Klisch J ( Department of Neuroradiology (J.K., C.S.), Helios General Hospital, Erfurt, Germany.); Strasilla C ( Department of Neuroradiology (J.K., C.S.), Helios General Hospital, Erfurt, Germany.); Berlis A ( Department of Diagnostic and Interventional Neuroradiology (A.B.), Klinikum Augsburg, Augsburg, Germany.); Patankar T ( MRI Department (T.P.), Leeds Teaching Hospitals National Health Service Trust, Leeds, UK.); Weber W ( Interventional Neuroradiology (W.W.), Ruhr University Medical Center, Bochum, Germany.); Behme D ( Departments of Radiology and Neuroradiology (D.B.), Klinikum Vest, Recklinghausen, Germany.); Jacobsen EA ( Interventional Neuroradiology (E.A.J.), Oslo University Hospital, Oslo, Norway.); Liebig T ( Interventional Neuroradiology (T.L.), Universitatsklinik Koeln, Köln, Germany.); Prothmann S ( Abteilung für Diagnostische und Interventionelle Neuroradiologie (S.P.), Klinikum rechts der Isar, Technische Universität München, München, Germany.); Cognard C ( Interventional Neuroradiology (C.C.), Centre Hospitalier Universitaire Hôpital Purpan, Toulouse, France.); Finkenzeller T ( Interventional Neuroradiology (T.F.), Klinikum Nürnberg Süd, Nürnberg, Germany.); Moret J ( From the Interventional Neuroradiology NEURI Center (J.C., C.M., J.M., L.S.), Beaujon Hospital, Clichy, France.); Spelle L ( From the Interventional Neuroradiology NEURI Center (J.C., C.M., J.M., L.S.), Beaujon Hospital, Clichy, France.) |
| Abstract |
BACKGROUND AND PURPOSE: The safety and efficiency of the dual-layer Woven EndoBridge (WEB) device has already been published. However, this international multicenter study sought to evaluate the safety of single-layer devices, which are the newest generation of the WEB intrasaccular flow-disrupter family. They have been designed to offer smaller-sized devices with a lower profile to optimize navigability and delivery, which may, in turn, broaden their range of use. MATERIALS AND METHODS: Data from all consecutive patients treated with a single-layer WEB device, in 10 European centers from June 2013 to May 2014 were included. Clinical presentations, technical details, intra- and perioperative complications, and outcomes at discharge were recorded. Clinical and angiographic data at last follow-up were also analyzed when available. RESULTS: Ninety patients with 98 WEB-treated aneurysms were included in this study. In 93 cases (95%), WEB placement was possible. Complete occlusion at the end of the procedure was obtained in 26 instances (26%). Additional treatment during the procedure (coiling and/or stent placement) was necessary in 12 cases (12.7%). Procedure-related complications occurred in 13 cases, leading to permanent neurologic deficits in 4 patients (4.4%). Early vascular imaging follow-up data were available for 44 patients (57%), with an average time interval of 3.3 months. Treatment-related morbidity and mortality rates at last follow-up were 2.2% and 1.1%, respectively. CONCLUSIONS: In this study, the feasibility and safety of the single-layer WEB device was comparable with that of the double-layer. However, further studies are needed to evaluate long-term efficacies. |
