NDLI: Combined Use of Mechanical Thrombectomy with Angioplasty and Stenting for Acute Basilar Occlusions with Underlying Severe Intracranial Vertebrobasilar Stenosis: Preliminary Experience from a Single Chinese Center.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Gao, F. Lo, W. T. Sun, X. Mo, D. P. Ma, N. Miao, Z. R.
Spatial Coverage	China
Description	Country affiliation: China Author Affiliation: Gao F ( From the Department of Interventional Neurology (F.G., X.S., D.P.M., N.M., Z.R.M.), Beijing Tiantan Hospital, Capital Medical University); Lo WT ( Department of Medicine (W.T.L.), Queen Elizabeth Hospital, Hong Kong, China.); Sun X ( From the Department of Interventional Neurology (F.G., X.S., D.P.M., N.M., Z.R.M.), Beijing Tiantan Hospital, Capital Medical University); Mo DP ( From the Department of Interventional Neurology (F.G., X.S., D.P.M., N.M., Z.R.M.), Beijing Tiantan Hospital, Capital Medical University); Ma N ( From the Department of Interventional Neurology (F.G., X.S., D.P.M., N.M., Z.R.M.), Beijing Tiantan Hospital, Capital Medical University); Miao ZR ( From the Department of Interventional Neurology (F.G., X.S., D.P.M., N.M., Z.R.M.), Beijing Tiantan Hospital, Capital Medical University)
Abstract	BACKGROUND AND PURPOSE: Acute basilar occlusions have a poor prognosis without recanalization. Many have underlying severe atherosclerotic intracranial stenosis coexisting with acute thrombosis, requiring treatment of both pathologies in the same session, though technical risks may be encountered. The purpose of this study was to evaluate the technical feasibility and safety of combined treatment by using stent retrievers for the thrombosis, together with angioplasty and stent placement for the underlying stenosis. MATERIALS AND METHODS: This was a retrospective review of 13 patients with basilar occlusions treated with thrombectomy by the Solitaire stent retriever and angioplasty and intracranial stent placement for underlying severe vertebrobasilar stenosis in the same session. Reperfusion was assessed in terms of the TICI score. Perioperative complications were recorded. Clinical outcomes were assessed by the NIHSS at discharge and the mRS on follow-up at 90 days. RESULTS: Of the 30 patients with acute basilar artery occlusions treated with stent retrievers during the study period, 18 had coexisting severe intracranial stenosis. Thirteen patients meeting the criteria for our study received combined mechanical thrombectomy and angioplasty with stent placement. The successful recanalization rate was 100%. Distal vessel embolizations occurred in 3 patients. There were 2 mortalities. On discharge, 10 patients (77%) had an improvement in NIHSS of ≥10 points. At 90 days, 6 patients (46%) had a good functional outcome with an mRS of ≤2. CONCLUSIONS: The combined use of mechanical thrombectomy with angioplasty and stent placement for acute basilar occlusions with underlying severe intracranial atherosclerotic stenosis is technically feasible and safe.
File Format	HTM / HTML
ISSN	01956108
e-ISSN	1936959X
Journal	American Journal of Neuroradiology
Issue Number	10
Volume Number	36
Language	English
Publisher	American Journal of Neuroradiology
Publisher Date	2015-10-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Neurology Discipline Radiology Angioplasty Stents Thrombectomy Vertebrobasilar Insufficiency Therapy Acute Disease Combined Modality Therapy Retrospective Studies
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Neurology (clinical)

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