NDLI: Soda consumption and the risk of stroke in men and women.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Bernstein, Adam M. de Koning, Lawrence Flint, Alan J. Rexrode, Kathryn M. Willett, Walter C.
Description	Country affiliation: United States Author Affiliation: Bernstein AM ( Wellness Institute of Cleveland Clinic, Lyndhurst, OH 44124, USA. bernsta2@ccf.org)
Abstract	BACKGROUND: Consumption of sugar-sweetened soda has been associated with an increased risk of cardiometabolic disease. The relation with cerebrovascular disease has not yet been closely examined. OBJECTIVE: Our objective was to examine patterns of soda consumption and substitution of alternative beverages for soda in relation to stroke risk. DESIGN: The Nurses' Health Study, a prospective cohort study of 84,085 women followed for 28 y (1980-2008), and the Health Professionals Follow-Up Study, a prospective cohort study of 43,371 men followed for 22 y (1986-2008), provided data on soda consumption and incident stroke. RESULTS: We documented 1416 strokes in men during 841,770 person-years of follow-up and 2938 strokes in women during 2,188,230 person-years of follow-up. The pooled RR of total stroke for ≥ 1 serving of sugar-sweetened soda/d, compared with none, was 1.16 (95% CI: 1.00, 1.34). The pooled RR of total stroke for ≥ 1 serving of low-calorie soda/d, compared with none, was 1.16 (95% CI: 1.05, 1.28). Compared with 1 serving of sugar-sweetened soda/d, 1 serving of decaffeinated coffee/d was associated with a 10% (95% CI: 1%, 19%) lower risk of stroke and 1 serving of caffeinated coffee/d with a 9% (95% CI: 0%, 17%) lower risk. Similar estimated reductions in risk were seen for substitution of caffeinated or decaffeinated coffee for low-calorie soda. CONCLUSIONS: Greater consumption of sugar-sweetened and low-calorie sodas was associated with a significantly higher risk of stroke. This risk may be reduced by substituting alternative beverages for soda.
File Format	HTM / HTML
ISSN	00029165
e-ISSN	19383207
DOI	10.3945/ajcn.111.030205
Journal	American Journal of Clinical Nutrition
Issue Number	5
Volume Number	95
Language	English
Publisher	American Society for Nutrition
Publisher Date	2012-05-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Nutritional Sciences Carbonated Beverages Stroke Epidemiology Dietary Sucrose Administration & Dosage Adverse Effects Energy Intake Multivariate Analysis Proportional Hazards Models Risk Factors Questionnaires Sweetening Agents Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Nutrition and Dietetics Medicine

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