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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Zang, Shanshan Zhuo, Qi Chang, Xiao Qiu, Guixing Wu, Zhihong Yang, Guang |
| Description | Country affiliation: China Author Affiliation: Zang S ( Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.); Zhuo Q ( Department of Orthopaedic Surgery, Chinese PLA General Hospital, Beijing 100853, China.); Chang X ( Department of Orthopaedics, Peking Union Medical College Hospital, Beijing 100730, China.); Qiu G ( Department of Orthopaedics, Peking Union Medical College Hospital, Beijing 100730, China.); Wu Z ( Department of Orthopaedics, Peking Union Medical College Hospital, Beijing 100730, China. Electronic address: wuzh3000@126.com.); Yang G ( Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China. Electronic address: yang_sunny@yahoo.com.) |
| Abstract | Bacterial cellulose (BC) has been proposed as a biomaterial applied in biomedical scope due to its good biocompatibility. Recent reports showed that human adipose-derived stem cells (HASCs) have become a new choice to be used as seeding cells in tissue engineering. The objective of this study is to explore the potential of using BC and HASCs as scaffold and seeding cells in bone tissue engineering. The osteogenic differentiation was investigated by Von Kossa, Alizarin Red, ALP cellular staining and RT-PCR. The results showed that HASCs took a successful osteogenic differentiation on BC. Moreover, the in vivo animal test also provided the confirmation of the repair ability of BC on damaged bone. In conclusion, the author demonstrates the osteogenic differentiation of HASCs on BC and the feasibility of using BC and HASCs as scaffold and seeding cells in bone tissue engineering. |
| File Format | HTM / HTML |
| ISSN | 01448617 |
| Volume Number | 104 |
| e-ISSN | 18791344 |
| Journal | Carbohydrate Polymers |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2014-04-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Biochemistry__semicolon__materials Discipline Science Adult Stem Cells Cytology Cellulose Pharmacology Osteogenesis Tissue Engineering Tissue Scaffolds Chemistry Acetobacter Adipose Tissue Drug Effects Animals Humans Rabbits Stem Cell Transplantation Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Materials Chemistry Polymers and Plastics |
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