NDLI: Fibula allograft propping as an effective treatment for early-stage osteonecrosis of the femoral head: a systematic review

Content Provider	Springer Nature : BioMed Central
Author	Yue, Ju’an Gao, He Guo, Xiaozhong Wang, Randong Li, Bing Sun, Qiang Liu, Wangyan Chen, Jiao Li, Yingnan
Abstract	Background Osteonecrosis of the femoral head (ONFH) causes severe hip dysfunction. Left untreated, 80% of patients experience femoral head collapse, and 65–70% of patients require total hip arthroplasty (THA). Therefore, effective treatment is very important for ONFH. Objective To examine the effectiveness of fibula allografting for the treatment of early-stage ONFH Methods A systematic review was conducted by searching PubMed, EMBASE, and Web of Science databases using “avascular necrosis” or “ischemic necrosis” or “osteonecrosis” and “femoral head” and “fibula*,” and checking the references of primary articles and reviews. Two independent authors completed the study selection separately. We extracted the following details from each article: characteristics of the patients, clinical efficacy evaluation (Harris hip score [HSS], radiographic outcomes, the rate of conversation to total hip arthroplasty [THA], and adverse effects). Results A total of 213 articles were selected from PubMed (n = 45), EMBASE (n = 77), Web of Science (n = 203), and other sources (n = 10). After checking the articles, five articles were included in the final analysis. The average age of patients involved in this review was 34.48 years. The studies investigated fibula allografts to treat ONFH in 394 hips with a mean follow-up of 49.06 months. HHS was improved from 62.73 to 86.94. Radiographic progression was found in 33.66% of hips. The failure rate of head-saving surgery by THA was 14.5%. No patients had serious postoperative complications. Limitations The number of articles included in the study was small, and all studies were single-center studies. Most studies were retrospective with a low level of evidence. Surgical procedures were not identical with different follow-up times. Conclusion Although there are some limitations to our approach, this systematic review supports fibula allografting as a simple, effective treatment for early-stage ONFH, which presents less postoperative complications, and has a satisfactory clinical effect. We consider it to be worthy of promotion as a therapy for ONFH.
Related Links	https://josr-online.biomedcentral.com/counter/pdf/10.1186/s13018-020-01730-6.pdf
Ending Page	7
Page Count	7
Starting Page	1
File Format	HTM / HTML
DOI	10.1186/s13018-020-01730-6
Journal	Journal of Orthopaedic Surgery and Research
Issue Number	1
Volume Number	15
Language	English
Publisher	BioMed Central
Publisher Date	2020-06-03
Access Restriction	Open
Subject Keyword	Orthopedics Surgical Orthopedics Fibula allograft Systematic review Femoral head Osteonecrosis
Content Type	Text
Resource Type	Article
Subject	Surgery Orthopedics and Sports Medicine
Journal Impact Factor	2.8/2023
5-Year Journal Impact Factor	3/2023

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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