NDLI: Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review and meta-analysis

Content Provider	Springer Nature : BioMed Central
Author	Li, Zizhan Wei, Xiao Shao, Zhongjun Liu, Huan Bai, Shizhu
Abstract	Background Vitamin D plays a crucial role in oral health, and its deficiency is associated to significant changes in oral health diseases. We aimed to explore the relationship between levels of 25-hydroxyvitamin D (25(OH) D) and dental caries in children. Methods Four electronic databases were searched by two investigators including PubMed, Embase, Web of Science, and Cochrane Library. Dental caries results were presented as either prevalence or based on the index of primary and permanent teeth/surfaces with decaying, missing, and filled areas, while vitamin D levels were determined through laboratory testing. Two researchers independently selected studies, collected information, assessed risk of bias, and evaluated the study quality. Any disagreements were resolved through discussion. Results A total of 13 studies were included, comprising 5 cross-sectional studies, 5 cohort studies, 3 case–control studies, all of which had high methodological quality. Our meta-analysis showed that children with vitamin D deficiency had a 22% higher risk of dental caries than those with normal vitamin D levels, with a relative risk (RR) of 1.22 and a 95% confidence interval (CI) of 1.18 to 1. 25. Further subgroup analysis according to the three types of studies showed that the risk of dental caries in children with vitamin D deficiency was higher than that in normal vitamin D level group (cohort studies: 62%; cross-sectional studies, 19%; and case–control studies, 5%). Additionally, according to age, subgroup analysis also showed that the risk of dental caries in children with vitamin D deficiency was higher than that in normal vitamin D level group (permanent teeth studies, 28%; deciduous teeth studies, 68%; and mixed dentition studies 8%). Conclusions Levels of 25 (OH) D have been found negatively associated with dental caries in children, indicating that low vitamin D levels may be considered a potential risk factor to this dental disease.
Related Links	https://bmcoralhealth.biomedcentral.com/counter/pdf/10.1186/s12903-023-03422-z.pdf
Ending Page	11
Page Count	11
Starting Page	1
File Format	HTM / HTML
ISSN	14726831
DOI	10.1186/s12903-023-03422-z
Journal	BMC Oral Health
Issue Number	1
Volume Number	23
Language	English
Publisher	BioMed Central
Publisher Date	2023-10-19
Access Restriction	Open
Subject Keyword	Dentistry Oral and Maxillofacial Surgery Dental caries Vitamin D Children Meta-analysis
Content Type	Text
Resource Type	Article
Subject	Dentistry
Journal Impact Factor	2.6/2023
5-Year Journal Impact Factor	3.2/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

A cross-sectional study on the association between vitamin D levels and caries in the permanent dentition of Korean children

Maternal smoking during pregnancy and early childhood dental caries in children: a systematic review and meta-analysis

The Most Common Vitamin D Receptor Polymorphisms (ApaI,FokI, TaqI, BsmI, and BglI) in Children with Dental Caries: A Systematic Review and Meta-Analysis

Childhood obesity in relation to risk of dental caries: a cumulative and dose-response systematic review and meta-analysis

Prevalence of dental caries in children and adolescents with type 1 diabetes: a systematic review and meta-analysis

Prevalence of dental caries in Pakistan: a systematic review and meta-analysis

Vitamin D deficiency and oral health: a systematic review of literature

Relationship between vitamin D status and caries experience in a group of Egyptian children: a cross-sectional study

Prevalence of dental caries and associated factors among primary school children in Ethiopia: systematic review and meta-analysis

Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review and meta-analysis

Similar Documents

A cross-sectional study on the association between vitamin D levels and caries in the permanent dentition of Korean children

Maternal smoking during pregnancy and early childhood dental caries in children: a systematic review and meta-analysis

The Most Common Vitamin D Receptor Polymorphisms (ApaI,FokI, TaqI, BsmI, and BglI) in Children with Dental Caries: A Systematic Review and Meta-Analysis

Childhood obesity in relation to risk of dental caries: a cumulative and dose-response systematic review and meta-analysis

Prevalence of dental caries in children and adolescents with type 1 diabetes: a systematic review and meta-analysis

Prevalence of dental caries in Pakistan: a systematic review and meta-analysis

Vitamin D deficiency and oral health: a systematic review of literature

Relationship between vitamin D status and caries experience in a group of Egyptian children: a cross-sectional study

Prevalence of dental caries and associated factors among primary school children in Ethiopia: systematic review and meta-analysis

Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review and meta-analysis