NDLI: Development and accuracy validation of a fat fraction imaging biomarker for sialadenitis in the parotid gland

Content Provider	Springer Nature : BioMed Central
Author	Lee, Ari Choi, Yoon Joo Jeon, Kug Jin Han, Sang-Sun Lee, Chena
Abstract	Background The diagnosis of sialadenitis, the most frequent disease of the salivary glands, is challenging when the symptoms are mild. In such cases, biomarkers can be used as definitive diagnostic indicators. Recently, biomarkers have been developed by extracting and analyzing pathological and morphological features from medical imaging. This study aimed to establish a diagnostic reference for sialadenitis based on the quantitative magnetic resonance imaging (MRI) biomarker IDEAL-IQ and assess its accuracy. Methods Patients with sialadenitis (n = 46) and control subjects (n = 90) that underwent MRI were selected. Considering that the IDEAL-IQ value is a sensitive fat fractional marker to the body mass index (BMI), all subjects were also categorized as under-, normal-, and overweight. The fat fraction of parotid gland in the control and sialadenitis groups were obtained using IDEAL-IQ map. The values from the subjects in the control and sialadenitis groups were compared in each BMI category. For comparison, t-tests and receiver operating characteristic (ROC) curve analyses were performed. Results The IDEAL-IQ fat faction of the control and sialadenitis glands were 38.57% and 23.69%, respectively, and the differences were significant. The values were significantly lower in the sialadenitis group (P), regardless of the BMI types. The area under the ROC curve (AUC) was 0.83 (cut-off value: 28.72) in patients with sialadenitis. The AUC for under-, normal-, and overweight individuals were 0.78, 0.81, and 0.92, respectively. Conclusions The fat fraction marker based on the IDEAL-IQ method was useful as an objective indicator for diagnosing sialadenitis. This marker would aid less-experienced clinicians in diagnosing sialadenitis.
Related Links	https://bmcoralhealth.biomedcentral.com/counter/pdf/10.1186/s12903-023-03024-9.pdf
Ending Page	6
Page Count	6
Starting Page	1
File Format	HTM / HTML
ISSN	14726831
DOI	10.1186/s12903-023-03024-9
Journal	BMC Oral Health
Issue Number	1
Volume Number	23
Language	English
Publisher	BioMed Central
Publisher Date	2023-06-01
Access Restriction	Open
Subject Keyword	Dentistry Oral and Maxillofacial Surgery Imaging biomarker Magnetic resonance imaging Sialadenitis Salivary gland Diagnostic imaging
Content Type	Text
Resource Type	Article
Subject	Dentistry
Journal Impact Factor	2.6/2023
5-Year Journal Impact Factor	3.2/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Quantitative evaluation of parotid gland dysfunction in patients with hyposalivation using magnetic resonance imaging mapping technique

A systematic review of methods to diagnose oral dryness and salivary gland function

Imaging the major salivary glands.

Does fasting during Ramadan increase the risk of the development of sialadenitis?

Therapeutic effect of intraductal saline irrigation in chronic obstructive sialadenitis

Diseases of the salivary glands in infants and adolescents

Primary Tubercular Sialadenitis - A Diagnostic Dilemma.

A rare case of parotid gland lipoma arising from the deep lobe of the parotid gland

Epithelial-myoepithelial carcinoma of the parotid gland: Clinicopathological aspect, diagnosis and surgical consideration

Development and accuracy validation of a fat fraction imaging biomarker for sialadenitis in the parotid gland

Similar Documents

Quantitative evaluation of parotid gland dysfunction in patients with hyposalivation using magnetic resonance imaging mapping technique

A systematic review of methods to diagnose oral dryness and salivary gland function

Imaging the major salivary glands.

Does fasting during Ramadan increase the risk of the development of sialadenitis?

Therapeutic effect of intraductal saline irrigation in chronic obstructive sialadenitis

Diseases of the salivary glands in infants and adolescents

Primary Tubercular Sialadenitis - A Diagnostic Dilemma.

A rare case of parotid gland lipoma arising from the deep lobe of the parotid gland

Epithelial-myoepithelial carcinoma of the parotid gland: Clinicopathological aspect, diagnosis and surgical consideration

Development and accuracy validation of a fat fraction imaging biomarker for sialadenitis in the parotid gland