NDLI: Equilibrium study of copper absorption to different types of soft contact lens

Content Provider	Springer Nature Link
Author	Shin, Sooim Choi, Moonsung
Copyright Year	2017
Abstract	To measure binding affinity of copper, one of the heavy metals in particulate matter (PM) was applied to soft contact lenses made of two different materials because contact lenses are readily exposed to PM. Copper binding to ionized silicon hydrogel lens yielded an equilibrium association constant K $_{a,eq}$ value of 14.03 μM without color change of lens, compared to that of 19.16 μM for copper binding to de-ionized hydrogel lenses with color change of lens. The results indicated that the color change of lens is not consistent with the concentration of cooper deposition on lens, and copper bound relatively stronger in ionized silicon hydrogel lens than in de-ionized hydrogel lens. Therefore, the continuous exposure of contact lenses to high PM levels might lead to heavy metal deposition on the lens, which would be detrimental to ocular health.
Starting Page	215
Ending Page	219
Page Count	5
File Format	PDF
ISSN	24680834
Journal	Journal of the Korean Society for Applied Biological Chemistry
Volume Number	60
Issue Number	2
e-ISSN	24680842
Language	English
Publisher	Springer Netherlands
Publisher Date	2017-04-03
Publisher Place	Dordrecht
Access Restriction	Subscribed
Subject Keyword	Hydrogel lens Particulate matter Equilibrium association constant Applied Microbiology Biological Techniques Binding affinity Copper Bioorganic Chemistry
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Biochemistry, Genetics and Molecular Biology

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