NDLI: Trafficking inhibition of bruceanol B as a radical-producing antibiotic

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Trafficking inhibition of bruceanol B as a radical-producing antibiotic

Content Provider	Springer Nature Link
Author	Hong, Quanchun Park, Se Pill Boo, Kyung Hwan Lee, Dong Sun Woo, Jin Kyu Cho, Somi K. Riu, Key Zung Lee, Doseung
Copyright Year	2003
Abstract	Bruceanol B, isolated from a soil microbe strain DS4, generated oxygen radicals in Bacillus subtilis lysates. Bruceanol B inhibited the trafficking of viral glycoprotein in virus-infected baby hamster kidney (BHK) cells. Bruceanol B also effectively inhibited syncytium formation in a dosedependent manner. However, glycoprotein synthesis was not affected by the compound. Results indicate that bruceanol B generating oxygen radical has inhibitory activity in the trafficking of viral glycoprotein of BHK cell.
Starting Page	299
Ending Page	301
Page Count	3
File Format	PDF
ISSN	17382203
Journal	Journal of the Korean Society for Applied Biological Chemistry
Volume Number	54
Issue Number	2
e-ISSN	2234344X
Language	English
Publisher	Springer-Verlag
Publisher Date	2003-01-01
Publisher Place	New York
Access Restriction	Subscribed
Subject Keyword	radical-generating antibiotic Applied Microbiology Biological Techniques bruceanol B Bioorganic Chemistry trafficking inhibition
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Biochemistry, Genetics and Molecular Biology

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