NDLI: Comparison of Clinical Outcomes of Anterior Versus Posterior Surgery in Treating Multi-segmental Cervical Degeneration

Content Provider	Springer Nature Link
Author	Wang, Qiang Cai, Jun Tao, Yuping Sun, Yu Li, Xiaolei Zhang, Zhiqiang Fang, Yongchao Wang, Jingcheng
Copyright Year	2014
Abstract	The purpose of this study is to compare clinical outcome of different surgical methods in treating multi-segmental cervical degeneration. Three hundred and sixty eight patients with multi-segmental cervical degeneration were retrospectively selected and divided into two groups with 184 cases in each based on different surgical methods: one group accepted surgeries from anterior surgical approach and the other group accepted surgeries from posterior surgical approach. Perioperative parameters including operative time, intraoperative blood loss and length of stay were compared between two groups. Patients were followed up after 1 week, 6 month, 10 months and 1 year after surgery. Cervical X-ray was retaken, and Japanese orthopaedic association (JOA) scores, neck disability index (NDI ) scores and numerical pain rating scale (NPRS ) scores were obtained for comparison. Samples from cervical disc were processed to detect cytokines level including IL-1, IL-6, TNF-α and MMP-3. Perioperative parameters including operative time, intraoperative blood loss and length of stay showed no significant difference (P < 0.05) between the two groups. JOA score, NDI scores and NPRS scores, all showed a significant improvement after the surgery in both methods, however, when comparing the two methods, no significant difference was found between two groups (P > 0.05), except that NDI scores in anterior surgical approach group were significantly lower than posterior surgical approach group at different follow-up time points (P < 0.05). The average height of fused vertebral bodies after surgery in two groups was significantly different from pre-operative height (P < 0.05), and angle loss in posterior surgical approach group was significantly higher than anterior surgical approach (P < 0.05), which was statistically different. Cytokines including IL-1, IL-6, TNF-α and MMP-3 in two groups had no statistical difference (P > 0.05). Anterior approach surgery and posterior approach surgery are both effective methods to treat multi-segmental cervical degeneration. Anterior approach had better clinical outcomes within 1-year follow-up.
Starting Page	1077
Ending Page	1082
Page Count	6
File Format	PDF
ISSN	10859195
Journal	Cell Biochemistry and Biophysics
Volume Number	71
Issue Number	2
e-ISSN	15590283
Language	English
Publisher	Springer US
Publisher Date	2014-10-21
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Multi-segment Cervical degeneration disease Anterior approach surgery Posterior approach surgery Biochemistry Pharmacology/Toxicology Biotechnology Cell Biology Biophysics and Biological Physics
Content Type	Text
Resource Type	Article
Subject	Cell Biology Medicine Biochemistry Biophysics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Comparison of Adjacent Segment Degeneration, Cervical Alignment, and Clinical Outcomes After One- and Multilevel Anterior Cervical Discectomy and Fusion.

Clinical Outcomes of Treating Cervical Adjacent Segment Disease by Anterior Cervical Discectomy and Fusion Versus Total Disc Replacement: A Systematic Review and Meta-Analysis

Posterior Trochanteric Osteotomy in Acetabular Fractures for 32 Cases

Adjacent segment disease after anterior cervical discectomy and fusion: Incidence and clinical outcomes of patients requiring anterior versus posterior repeat cervical fusion

Adjacent segment disease after anterior cervical discectomy and fusion: Incidence and clinical outcomes of patients requiring anterior versus posterior repeat cervical fusion

Repositioning Suture of the Erector Spinae Muscle for Lumbar Spine Surgery via the Posterior Approach: A Prospective Randomized Study

Clinical Value of Preventative Ileostomy Following Ultra-Low Anterior Rectal Resection

Comparison in Clinical Outcome of Two Surgical Treatments in Degenerative Scoliosis

Comparison study of clinical outcomes and sagittal alignment improvement between anterior and posterior fusion techniques for multilevel cervical spondylotic myelopathy

Comparison of Clinical Outcomes of Anterior Versus Posterior Surgery in Treating Multi-segmental Cervical Degeneration

Similar Documents

Comparison of Adjacent Segment Degeneration, Cervical Alignment, and Clinical Outcomes After One- and Multilevel Anterior Cervical Discectomy and Fusion.

Clinical Outcomes of Treating Cervical Adjacent Segment Disease by Anterior Cervical Discectomy and Fusion Versus Total Disc Replacement: A Systematic Review and Meta-Analysis

Posterior Trochanteric Osteotomy in Acetabular Fractures for 32 Cases

Adjacent segment disease after anterior cervical discectomy and fusion: Incidence and clinical outcomes of patients requiring anterior versus posterior repeat cervical fusion

Adjacent segment disease after anterior cervical discectomy and fusion: Incidence and clinical outcomes of patients requiring anterior versus posterior repeat cervical fusion

Repositioning Suture of the Erector Spinae Muscle for Lumbar Spine Surgery via the Posterior Approach: A Prospective Randomized Study

Clinical Value of Preventative Ileostomy Following Ultra-Low Anterior Rectal Resection

Comparison in Clinical Outcome of Two Surgical Treatments in Degenerative Scoliosis

Comparison study of clinical outcomes and sagittal alignment improvement between anterior and posterior fusion techniques for multilevel cervical spondylotic myelopathy

Comparison of Clinical Outcomes of Anterior Versus Posterior Surgery in Treating Multi-segmental Cervical Degeneration