NDLI: Molecular epidemiology of PRRSV from China’s Guangxi Province between 2007 and 2009

Content Provider	Springer Nature Link
Author	Zhang, Hong Yun Liang, Jing Jing Meng, Xian Ming Li, Hui Yang, Jian Su, Li Juan Zhang, Hong Pu Xie, Lin Juan He, Xiao Xia Li, Yan Sheng Yin, Shan Li, Xiao Quan Li, Xiao ning Luo, Ting Rong
Copyright Year	2012
Abstract	Porcine reproductive and respiratory syndrome (PRRS) is considered to be one of the most important infectious diseases affecting livestock. This study used gene sequence analysis of ORF5 and Nsp2 to determine the molecular epidemiology of PRRSV in different parts of the Guangxi province of China. These genes were selected due to their extensive variation within the genome. Out of 189 samples from animals suspected to have PRRS, 145 were PRRSV RNA positive. ORF5 and Nsp2 gene sequence analysis of 31 of these samples showed that all of the Guangxi isolates were of type 2. A phylogenetic tree analysis based on ORF5 showed that the Guangxi isolates were divided into two groups. Most of these were closely related to highly pathogenic strains, showing a 30 amino acid deletion at positions 481 and 533–561 of Nsp2, but an additional unique isolate (GXNN06) possessed a further four amino acid deletion at positions 485–488 of Nsp2.
Starting Page	71
Ending Page	80
Page Count	10
File Format	PDF
ISSN	09208569
Journal	Virus Genes
Volume Number	46
Issue Number	1
e-ISSN	1572994X
Language	English
Publisher	Springer US
Publisher Date	2012-09-25
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Porcine reproductive and respiratory syndrome virus (PRRSV) ORF5 Nsp2 Molecular epidemiology Medical Microbiology Virology Plant Sciences
Content Type	Text
Resource Type	Article
Subject	Virology Genetics Medicine Molecular Biology

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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