NDLI: The relationship of surface roughness and cell response of chemical surface modification of titanium

Content Provider	Springer Nature Link
Author	Zareidoost, Amir Yousefpour, Mardali Ghaseme, Behrooz Amanzadeh, Amir
Copyright Year	2012
Abstract	Implant surface topography influences osteoblastic proliferation, differentiation and extracellular matrix protein expressions. Previous researches proved that chemical surface modification of titanium implants could be used to improve Bone-to-implant contact. In this study, the surface topography, chemistry and biocompatibility of polished titanium surfaces treated with mixed solution of three acids containing HCl, HF and H$_{3}$PO$_{4}$ with different etched conditions for example concentration, time and addition of calcium chloride were studied. Osteoblast cells (MG-63) were cultured on different groups of titanium surfaces. In order to investigate titanium surfaces, SEM, AFM and EDS analyses were carried out. The results showed that surfaces treated with HCl–HF–H$_{3}$PO$_{4}$ had higher roughness, lower cytotoxicity level and better biocompatibility than controls. Moreover, addition of calcium chloride into mixed solution of three acids containing HCl, HF and H$_{3}$PO$_{4}$ is an important, predominant and new technique for obtaining biofunction in metals for biomedical use including dentistry.
Starting Page	1479
Ending Page	1488
Page Count	10
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	23
Issue Number	6
e-ISSN	15734838
Language	English
Publisher	Springer US
Publisher Date	2012-03-30
Publisher Place	Boston
Access Restriction	Subscribed
Subject Keyword	Metallic Materials Surfaces and Interfaces, Thin Films Polymer Sciences Biomaterials Characterization and Evaluation of Materials Ceramics, Glass, Composites, Natural Methods
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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