NDLI: Supercritical CO$_{2}$ extraction of fatty acids, phenolics and fucoxanthin from freeze-dried Sargassum muticum

Content Provider	Springer Nature Link
Author	Conde, Enma Moure, Andrés Domínguez, Herminia
Copyright Year	2014
Abstract	The potential of compressed CO$_{2}$ for the extraction of valuable compounds (fatty acids, phenolic compounds and fucoxanthin) from the brown alga, Sargassum muticum, has been explored. Pure supercritical CO$_{2}$ (scCO$_{2}$) allowed the extraction of up to 15 % of the ethanol extractables, with the highest yield attained at 10 MPa and 50 °C. The addition of ethanol as cosolvent increased by three both the extraction yields and the radical scavenging activity, and by 90 times the fucoxanthin yield. The extracts obtained with pure carbon dioxide contained higher proportion of ω3 fatty acids than those using with conventional solvents, showing an ω6/ω3 ratio of 2.12 and 2.84 for pure and ethanol modified scCO$_{2}$, respectively. Selected extracts showed antibrowning activity on B16F10 murine cells and inhibition of lipogenesis in SW872 liposarcoma cells, although cytotoxic effects were observed at 50 μg mL$^{−1}$.
Starting Page	957
Ending Page	964
Page Count	8
File Format	PDF
ISSN	09218971
Journal	Journal of Applied Phycology
Volume Number	27
Issue Number	2
e-ISSN	15735176
Language	English
Publisher	Springer Netherlands
Publisher Date	2014-08-08
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Sargassum muticum Phaeophyta Supercritical CO$_{2}$ Fucoxanthin Fatty acids Radical scavenging Plant Sciences Freshwater & Marine Ecology Plant Physiology Ecology
Content Type	Text
Resource Type	Article
Subject	Plant Science Aquatic Science

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