NDLI: Adherence to the Mediterranean diet and nasopharyngeal cancer risk in Italy

Content Provider	Springer Nature Link
Author	Turati, Federica Bravi, Francesca Polesel, Jerry Bosetti, Cristina Negri, Eva Garavello, Werner Taborelli, Martina Serrai, Diego Libra, Massimo Montella, Maurizio Decarli, Adria Ferraroni, Monica La Vecchia, Carlo
Copyright Year	2017
Abstract	Few studies investigated the role of diet on nasopharyngeal cancer (NPC) risk in non-endemic areas. The aim of this study was to assess the association between adherence to the traditional Mediterranean diet and NPC risk in a southern European low-risk population.We conducted a hospital-based case-control study in Italy, including 198 histologically confirmed NPC cases and 594 matched controls. Dietary habits were collected by means of a validated food-frequency questionnaire, including 83 foods, food groups, or beverages. Adherence to the traditional Mediterranean diet was assessed through a Mediterranean Diet Score (MDS), based on nine dietary components characterizing this dietary profile, i.e., high intake of vegetables, fruits and nuts, cereals, legumes, and fish; low intake of dairy products and meat; high monounsaturated to saturated fatty acid ratio; and moderate alcohol intake. We estimated odds ratios (ORs) of NPC, and the corresponding 95% confidence intervals (CIs), for increasing MDS (i.e., increasing adherence) using multiple logistic regression models, adjusted for major confounding factors.As compared to MDS ≤ 4, the ORs of NPC were 0.83 (95% CI: 0.54–1.25) for MDS of 5 and 0.66 (95% CI: 0.44–0.99) for MDS ≥ 6, with a significant trend of decreasing risk (p 0.043). The corresponding population attributable fraction was 22%, indicating that 22% of NPC cases in this population would be avoided by shifting all subjects to a score ≥6.Our study supports a favorable role of the Mediterranean diet on NPC risk.
Starting Page	89
Ending Page	95
Page Count	7
File Format	PDF
ISSN	09575243
Journal	Cancer Causes & Control
Volume Number	28
Issue Number	2
e-ISSN	15737225
Language	English
Publisher	Springer International Publishing
Publisher Date	2017-02-02
Publisher Place	Cham
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Case–control study Mediterranean diet Nasopharyngeal cancer Risk factor Prevention Cancer Research Biomedicine Oncology Public Health Epidemiology Hematology
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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