NDLI: Diet and risk of adult leukemia: a multicenter case

Content Provider	Springer Nature Link
Author	Liu, Ping Holman, C. D’Arcy J. Jin, Jie Zhang, Min
Copyright Year	2015
Abstract	Epidemiologic studies on diet and leukemia risk have shown inconsistent results. This study examined the associations between dietary factors and the risk of adult leukemia in Chinese populations.A multicenter case–control study was conducted in southeast and northeast China between 2008 and 2013. It included 442 incident cases with hematologically confirmed leukemia and 442 controls, individually match to cases by gender, birth quinquennium, and study site. Information on diet was sought from face-to-face interviews using a validated and reliable 103-item food frequency questionnaire. Odds ratios (ORs) and confidence intervals (CIs) were estimated by conditional logistic regression.Vegetables intake was associated with decreased risk of adult leukemia, with a significant dose–response relationship and adjusted OR of 0.30 (95 % CI 0.18–0.50) for the highest versus the lowest quartiles intake. Compared with non-consumers, the adjusted OR was 0.51 (95 % CI 0.29–0.93) for those who consumed milk at the highest tertile. Intakes of fruits, red meat, poultry, and fish were not associated with the risk. Dietary nutrients, including dietary fiber, carotenoids, vitamins B1, B2, and C, niacin, and folate, were significantly associated with reduced risks. Elevated risk was related to dietary intake animal fat and dietary habits with frequent intakes of fat, deep-fried, and smoked foods ( p for trend <0.05).Our findings suggest that diets rich in vegetables and adequate amount of milk reduce the risk of adult leukemia, whereas diets preferring fat, deep-fried, and smoked foods increase the risk in Chinese populations.
Starting Page	1141
Ending Page	1151
Page Count	11
File Format	PDF
ISSN	09575243
Journal	Cancer Causes & Control
Volume Number	26
Issue Number	8
e-ISSN	15737225
Language	English
Publisher	Springer International Publishing
Publisher Date	2015-06-14
Publisher Place	Cham
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Diet Foods Nutrients Adult leukemia Case–control Cancer Research Biomedicine general Oncology Public Health Epidemiology Hematology
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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