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| Content Provider | Springer Nature Link |
|---|---|
| Author | Rosato, Valentina Edefonti, Valeria Bravi, Francesca Bosetti, Cristina Bertuccio, Paola Talamini, Renato Dal Maso, Luigi Montella, Maurizio Ferraroni, Monica La Vecchia, Carlo Decarli, Adria |
| Copyright Year | 2014 |
| Abstract | The role of various foods and nutrients, and their combinations, on prostate cancer risk remains largely undefined. We addressed therefore the issue of complex dietary patterns.We analyzed data from an Italian case–control study, including 1,294 men with prostate cancer and 1,451 hospital controls. We carried out an exploratory principal component factor analysis on 28 selected nutrients in order to identify dietary patterns. We estimated odds ratios (ORs) and corresponding confidence intervals (CIs) using logistic regression models on quintiles of factor scores, adjusting for major confounding variables.We identified five dietary patterns, labeled “Animal Products,” “Vitamins and Fiber,” “Starch-rich,” “Vegetable Unsaturated Fatty Acids (VUFA),” and “Animal Unsaturated Fatty Acids (AUFA).” We found positive associations between prostate cancer and “Animal Products” (OR for the highest vs. the lowest score quintile: 1.51, 95 % CI 1.16–1.96), “Starch-rich” (OR 1.50, 95 % CI 1.16 1.93), and “AUFA” (OR 1.32, 95 % CI 1.02–1.70) patterns. No significant associations emerged with “Vitamins and Fiber” (OR 0.93) and “VUFA” (OR 1.16) patterns.Our findings suggest that a diet rich in animal products, including several types of meat and dairy products, as well as of (refined) cereals and sugars has an unfavorable role on prostate cancer. |
| Starting Page | 525 |
| Ending Page | 532 |
| Page Count | 8 |
| File Format | |
| ISSN | 09575243 |
| Journal | Cancer Causes & Control |
| Volume Number | 25 |
| Issue Number | 4 |
| e-ISSN | 15737225 |
| Language | English |
| Publisher | Springer International Publishing |
| Publisher Date | 2014-02-11 |
| Publisher Place | Cham |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Case–control study Dietary patterns Factor analysis Nutrients Prostate cancer Risk factor Cancer Research Biomedicine general Oncology Public Health Epidemiology Hematology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cancer Research Oncology |
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