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| Content Provider | Springer Nature Link |
|---|---|
| Author | Pizzo, Francesca Frauscher, Birgit Ferrari Marinho, Taissa Amiri, Mina Dubeau, Francois Gotman, Jean |
| Copyright Year | 2016 |
| Abstract | To evaluate the possibility of detecting fast ripples (FRs) on the surface EEG of patients with focal pharmacoresistant epilepsy, and to investigate the relationship between scalp FRs and localization of the seizure onset zone (SOZ). We included 10 patients undergoing combined surface–intracranial EEG with ≥10 spikes in the surface EEG during the first 30 consecutive minutes of N3 sleep. FRs (≥4 consecutive oscillations above 250 Hz with an amplitude clearly exceeding that of the background) on the surface EEG (F3-C3, C3-P3, Fz-Cz, Cz-Pz, F4-C4, C4-P4) were visually marked, and verified by two EEG experts. FRs were categorized as related to the SOZ, if localized in the brain lobe of the SOZ. Low-amplitude FRs with a rate of 0.09/min were found in 6/10 patients: two exhibited events related to the SOZ, three showed no relationship with the SOZ, and in one patient the SOZ was not identified. It may be possible to detect FRs with surface EEG using subdermal electrodes in patients with focal epilepsy. The relationship between surface FRs and the SOZ remains unclear. Future studies aiming at a higher spatial EEG coverage are needed to elucidate their significance. |
| Starting Page | 358 |
| Ending Page | 367 |
| Page Count | 10 |
| File Format | |
| ISSN | 08960267 |
| Journal | Brain Topography |
| Volume Number | 29 |
| Issue Number | 3 |
| e-ISSN | 15736792 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2016-02-26 |
| Publisher Place | New York |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Fast ripples Scalp EEG Subdermal electrodes Focal epilepsy High frequency oscillations Neurosciences Psychiatry Neurology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neurology Anatomy Radiology, Nuclear Medicine and Imaging Neurology (clinical) Radiological and Ultrasound Technology |
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