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| Content Provider | Springer Nature Link |
|---|---|
| Author | Wang, Zhaofei Fu, Qiang Cao, Jianguo Deng, Xiyun Li, Yue Wang, Qiaofeng Zheng, Zhaofen |
| Copyright Year | 2016 |
| Abstract | To evaluate the transduction efficiency of human umbilical cord-derived, late endothelial progenitor cells late (HUCB-late EPCs) with nine recombinant adeno-associated virus (rAAV) serotypes and the ability of proliferation and migration of the cells after transduction.rAAV2 and rAAV6 showed a greater ability than other serotypes to transduce late EPCs (P < 0.05). After transduction, cell proliferation ability weakened (P < 0.05), but the ability of migration to stromal cell-derived factor (SDF-1) unchanged.There is an advantage of choosing the optimal rAAV serotype as a gene vector to alter the biologic characteristics of late EPCs. |
| Starting Page | 1073 |
| Ending Page | 1079 |
| Page Count | 7 |
| File Format | |
| ISSN | 01415492 |
| Journal | Biotechnology Letters |
| Volume Number | 38 |
| Issue Number | 7 |
| e-ISSN | 15736776 |
| Language | English |
| Publisher | Springer Netherlands |
| Publisher Date | 2016-03-14 |
| Publisher Place | Dordrecht |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Human umbilical cord-derived late endothelial progenitor cells (HUCB-late EPCs) Recombinant adeno-associated virus (rAAV) Transduction efficiency Microbiology Biotechnology Applied Microbiology Biochemistry |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Bioengineering Applied Microbiology and Biotechnology Biotechnology |
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