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Quantitative coronary angiographic and intravascular ultrasound assessment of a new nonarticulated stent: report from the Advanced Cardiovascular Systems MultiLink stent pilot study.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Hermiller, James Bernard Robertson, Lindsay |
| Copyright Year | 1998 |
| Abstract | OBJECTIVES The purpose of this study was to evaluate the safety, feasibility, optimal deployment technique and 1-year clinical outcome for the Advanced Cardiovascular Systems (ACS) MultiLink stent. BACKGROUND Optimal stent deployment assessed by quantitative coronary angiography and intravascular ultrasound (IVUS) is associated with improved clinical outcome. METHODS Forty-nine consecutive patients with a discrete stenosis in a native coronary artery 3 to 4 mm in diameter were treated with the new, balloon-expandable ACS MultiLink stent. Stent expansion was assessed in all patients using quantitative coronary angiography and serial IVUS imaging after 8-, 12- and 16-atm inflations. Clinical follow-up was obtained at 30 days and 1 year. RESULTS All 49 patients had successful placement of a MultiLink stent without death, emergency coronary artery bypass graft surgery or Q wave myocardial infarction. After placement of the MultiLink stent, the minimal lumen diameter increased from 1.24 to 2.98 mm (p < 0.001), and diameter stenosis decreased from 61% to 7% (p = 0.001). Minimal lumen cross-sectional area by IVUS increased progressively after 8, 12 and 16 atm (5.6 to 6.8 to 7.4 mm2, respectively, p < 0.001). However, only 64% of stents achieved a lumen/reference area ratio > or = 70%. No adverse clinical events occurred by 30 days, and by 1 year only one patient (2.0%) required revascularization of the stented artery. CONCLUSIONS Treatment of stenoses in native coronary arteries with the MultiLink stent is associated with a high success rate and a low incidence of adverse events by 1 year, despite the fact that the majority of stents did not meet IVUS-defined criteria for "optimal stenting" derived from first-generation devices. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.onlinejacc.org/content/accj/31/1/50.full.pdf |
| PubMed reference number | 9426017v1 |
| Volume Number | 31 |
| Issue Number | 1 |
| Journal | Journal of the American College of Cardiology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Adverse event Arterial system Aspirin Cardiovascular Diseases Cessation of life Coronary Artery Bypass Surgery Cyclosporine Deploy Diameter (qualifier value) Disseminated Intravascular Coagulation Forty Nine Inner Diameter Intravascular ultrasound Ludia sp. Schatz et al. 3608 Myocardial Infarction PNMA2 gene Patients Quantitative Coronary Angiography Stenosis Stent Device Component Stent, device Structure of lumen of body system Units Of Measure - lumen Warfarin angiogram revascularization |
| Content Type | Text |
| Resource Type | Report |
