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Six-month clinical and angiographic outcome after successful excimer laser angioplasty for in-stent restenosis.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Köster, Ralf Kaehler, Jan Terres, Wolfram Reimers, Jacobus Baldus, Stephan Hartig, Dennis P. P. Berger, Juergen Meinertz, Thomas |
| Copyright Year | 2000 |
| Abstract | OBJECTIVES This study evaluated the clinical and angiographic six-month follow-up after excimer laser coronary angioplasty (ELCA) for restenosed coronary stents. BACKGROUND Excimer laser coronary angioplasty has recently been shown to be safe and efficient for the treatment of in-stent restenosis. METHODS Ninety-six consecutive patients successfully treated with ELCA within 141 stents were included in a six-month clinical and angiographic follow-up. RESULTS During follow-up there was one sudden death and one patient with documented myocardial infarction. Angina pectoris classified as > or = Canadian Cardiovascular Society II reoccurred in 49 patients. Follow-up angiography was obtained in 89 patients (93%) with 133 stents. Quantitative coronary angiography revealed a mean diameter stenosis of 77 +/- 10% before intervention, 41 +/- 12% after laser treatment and 11% +/- 12% after adjunctive percutaneous transluminal coronary angioplasty (p < 0.001). Six months after ELCA the mean diameter stenosis had increased to 60 +/- 26% (p < 0.001). A > or =50% diameter stenosis was present in 48 patients (54%); in 24 of these patients diameter stenosis was > or =70%. Total occlusions occurred in an additional 10 patients (11%). There was a trend toward an increased recurrent restenosis rate in patients with diabetes mellitus and long lesions or total occlusions (p = 0.059). Forty-eight patients (50%) received medical treatment after six months. Reinterventions were necessary in 30 patients (31%), and coronary artery bypass surgery was performed in 17 patients (18%). Event-free survival was 50%. CONCLUSIONS Excimer laser angioplasty for in-stent restenosis was associated with a high incidence of recurrent restenosis in this group of patients, suggesting that this technique is unlikely to reduce recurrent in-stent restenosis and that other approaches are necessary. |
| Starting Page | 69 |
| Ending Page | 74 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.onlinejacc.org/content/accj/36/1/69.full.pdf |
| PubMed reference number | 10898415v1 |
| Volume Number | 36 |
| Issue Number | 1 |
| Journal | Journal of the American College of Cardiology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Adjunctive Orthodontic Procedure Angina Pectoris Angioplasty, Balloon Angioplasty, Balloon, Coronary Angioplasty, Laser Brachytherapy Cardiology discipline Cardiovascular Diseases Classification Coronary Artery Bypass Surgery Coronary Artery Disease Coronary angiography Diabetes Mellitus Diameter (qualifier value) Disseminated Intravascular Coagulation Document completion status - Documented Follow-Up Report Forty Nine Large Lasers, Excimer Mean Diameter Myocardial Infarction Obstruction Patients Percutaneous Transluminal Coronary Angioplasty STENT, CORONARY Scientific Publication Stenosis Stent Device Component Stent, device Sudden death Tissue Growth Tumor Debulking angiogram benefit restenosis |
| Content Type | Text |
| Resource Type | Article |
