NDLI: Osteonecrose dos maxilares associada ao uso de bifosfonatos: uma revisão de literatura

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Osteonecrose dos maxilares associada ao uso de bifosfonatos: uma revisão de literatura

Content Provider	Semantic Scholar
Author	Barin, Luisa Machado Pillusky, Fernanda Maia Pasini, Marcela Mozzaquatro Danesi, Cristiane Cademartori
Copyright Year	2016
Abstract	Bisphosphonates (BPS) are antiresorptive agents routinely used in the management of bone diseases and metastatic malignancies neoplasm. Its mechanism of action inhibits the osteoclastic and angiogenic activity of bone tissue. However, its chronic use can raise Bisphosphonate-Related Osteonecrosis of the Jaws (BRONJ), mainly in patients submitted to previous trauma. This study aims to review therapeutic approaches of these patients, focusing on prevention and treatment of these pathologies. The literature has presented various proposals to treat the BRONJ, but sometimes it’s controversial. The treatment of these pathologies has been challenging, once the protocols are not always effective to control this condition. Thus, previously of BFS therapeutic, the health professional should realize all the needed procedures to adequate the oral environment of these patients, as well as to maintain a rigorous attendance of your oral condition. It’s essential the multidisciplinary approach between physician and dental surgeon to manage these patients. Descriptors: Odontology. Diphosphonates. Mandible. Maxilla. Therapeutics. * Doutoranda do Curso de Pós-graduação de Ciências Odontológicas com ênfase em Patologia Bucal pela UFSM, RS, Brasil. (luisambarin@hotmail.com) * Mestre em Ciências Odontológicas com ênfase em Patologia Bucal pela UFSM, RS, Brasil. (fernandampillusky@hotmail.com, marcelam4p@gmail.com) *** Professora Doutora Adjunta do Departamento de Patologia da UFSM, RS, Brasil. (cristianedanesi@gmail.com)
Starting Page	126
Ending Page	126
Page Count	1
File Format	PDF HTM / HTML
DOI	10.26843/ro_unicid.v28i2.222
Volume Number	28
Alternate Webpage(s)	http://publicacoes.unicid.edu.br/index.php/revistadaodontologia/article/viewFile/222/120
Alternate Webpage(s)	https://doi.org/10.26843/ro_unicid.v28i2.222
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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