NDLI: Osteonecrose dos Maxilares Associada ao Uso de Bisfosfonatos: Revisão da Literatura e Apresentação de um Caso Clínico.

Please wait, while we are loading the content...

Osteonecrose dos Maxilares Associada ao Uso de Bisfosfonatos: Revisão da Literatura e Apresentação de um Caso Clínico.

Content Provider	Semantic Scholar
Author	Souza, Leandro Napier De Souza, Ana Cristina Rodrigues Antunes De Mari, Vanessa Flávia Arruda Borges, Ana Luiza Vilela Alvarenga, Rodrigo López
Copyright Year	2009
Abstract	Resumo Os bisfosfonatos sao medicamentos amplamente administrados a pacientes portadores de câncer de mama e prostata com metastases osseas, mieloma multiplo, osteoporose, doenca de Paget, hipercalcemia maligna e outras lesoes osseas metastaticas. A droga diminui a reabsorcao ossea, inibindo a actividade osteoclastica e o recrutamento de osteoclastos, promovendo a apoptose destes. A osteonecrose dos maxilares associada ao uso de bisfosfonatos tem sido relatada principalmente em pacientes submetidos a intervencoes odontologicas invasivas, como exodontias, cirurgias a retalho, endodontias, dentre outras. O presente estudo teve como objectivo realizar uma revisao de literatura sobre o assunto, levando em consideracao os factores etiologicos, os mecanismos de accao destes medicamentos, seus efeitos adversos e possiveis tratamentos, alem de descrever um caso clinico. Tendo em vista a dificuldade do tratamento e ao risco de intervencoes cirurgicas, pacientes que necessitam de medicamentos da classe dos bisfosfonatos devem, se possivel, ser submetidos a um exame odontologico criterioso, no qual todos os procedimentos necessarios sejam realizados previamente ao seu uso, diminuindo-se assim, os riscos da ocorrencia de osteonecrose.
Starting Page	229
Ending Page	236
Page Count	8
File Format	PDF HTM / HTML
DOI	10.1016/S1646-2890(09)70023-8
Volume Number	50
Alternate Webpage(s)	http://www.scielo.br/pdf/rbr/v51n4/v51n4a12.pdf
Alternate Webpage(s)	http://administracao.spemd.pt/app/assets/imagens/files_img/1_19_5a36482ee2777.pdf
Alternate Webpage(s)	https://doi.org/10.1016/S1646-2890%2809%2970023-8
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in