NDLI: The NMDA antagonist MK-801 blocks light effect on melatonin receptor density in rat suprachiasmatic nuclei

Content Provider	Semantic Scholar
Author	Gauer, François Masson-Pévet, Mireille Pevet, Paul
Copyright Year	1994
Abstract	In pinealectomized rats, melatonin receptor density in the suprachiasmatic nuclei was recently shown to be strongly decreased during the dark period. Furthermore, a one-hour long light pulse is able to reverse this dark-induced decrease. We demonstrate here that this effect of a light-pulse during night time is blocked by prior application of the NMDA receptor antagonist MK-801. These results show that the light effect on melatonin receptor density in the SCN is mediated by activation of NMDA-type receptors.
Starting Page	24
Ending Page	26
Page Count	3
File Format	PDF HTM / HTML
DOI	10.1016/0304-3940(94)90595-9
PubMed reference number	8084491
Journal	Medline
Volume Number	171
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/0304394094905959
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/0304394094905959?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://doi.org/10.1016/0304-3940%2894%2990595-9
Journal	Neuroscience Letters
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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The NMDA antagonist MK-801 blocks light effect on melatonin receptor density in rat suprachiasmatic nuclei